CLK4

Gene Symbol	CLK4
Entrez Gene	57396
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	CDC-like kinase 4
Other Description	dual specificity protein kinase CLK4|protein serine threonine kinase Clk4
Swissprots	Q9HAZ1
Accessions	EAW53831 EAW53832 Q9HAZ1 AF294429 AAG10074 AK294921 BAH11925 AK304614 BAH14226 AK308578 AK308674 AK308879 AK309215 AK310427 AK311485 BC015942 BC034633 AAH34633 BC046211 BC063116 BC065732 AAH65732 BC136261 AAI36262 BC143538 BC143547 AAI43548 BC151233 BX647323 CB127989 CR749504 CAH18325 XM_005265947 XP_005266004 XM_005265948 XP_005266005 XM_005265949 XP_005266006 XM_006714895 XP_006714958 XM_006714896 XP_006714959 XM_011534601 XP_011532903 XM_011534602 XP_011532904 XM_011534603 XP_011532905 XR_427807 NM_020666 NP_065717
Function	Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates SRSF1 and SRSF3. Required for the regulation of alternative splicing of MAPT/TAU. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells. {ECO:0000269|PubMed:11170754, ECO:0000269|PubMed:19168442}.
Subcellular Location	Nucleus {ECO:0000250}.
Tissue Specificity	Expressed in liver, kidney, heart, muscle, brain and endothelial cells. {ECO:0000269|PubMed:11170754, ECO:0000269|PubMed:19168442}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CLK4 full length protein - ab163542 from Abcam Category Protein Source Wheat germ Species Human

Human CLK4 protein fragment - ab163543 from Abcam Category Protein Source Wheat germ Species Human

CLK4 Antibody Blocking Peptide - LS-E3436 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CLK4 Antibody Blocking Peptide - LS-E10671 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CLK4 Antibody Blocking Peptide - LS-E10670 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human CLK4 Protein - H00057396-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human CLK4 Protein - H00057396-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

CLK4 - H00057396-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CLK4 - H00057396-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CLK4 - H00057396-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CLK4 - H00057396-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

CLK4 - P5529 from Acris Antibodies Category Protein Prices $840.00 Sizes 5 µg Species Human

CLK4 Protein, active, 250 µg - 14-917M from EMD Millipore Category Protein Prices $2,544.00 Sizes 250 µg also available in 10μg size as catalog # 14-917 and in bulk as catalog # 14-917-k. Source N-terminal 6His-tagged, recombinant, human CLK4 amino acids 128-end expressed by baculovirus in Sf21 insect cells.

CLK4 Protein, active, 10 µg - 14-917 from EMD Millipore Category Protein Prices $318.00 Sizes 10 µg also available in 250μg size as catalog # 14-917m and in bulk as catalog # 14-917-k. Source N-terminal 6His-tagged, recombinant, human CLK4 amino acids 128-end expressed by baculovirus in Sf21 insect cells.

CLK4 Protein, active, 0 0 - 14-917-K from EMD Millipore Category Protein Source N-terminal 6His-tagged, recombinant, human CLK4 amino acids 128-end expressed by baculovirus in Sf21 insect cells. Species Human

Recombinant Human Dual specificity protein kinase CLK4(CLK4) - CSB-YP875708HU CSB-EP875708HU CSB-BP875708HU CSB-MP875708HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Active human CLK4 protein fragment - ab204144 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

CLK4 Recombinant Protein Antigen - NBP2-47505PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

CLK4-Antibody-N-term-Blocking-Peptide - BP7532a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CLK4 Peptide, Human - M34GP03295H from Creative Peptides Category Peptide Source Synthetic. Species Human

Dual specificity protein kinase CLK4 (CLK4), Recombinant Protein - MBS1458768 from MyBioSource Category Protein Prices $1,265.00, $1,265.00, $1,485.00, $1,485.00, $2,070.00, $2,070.00, $2,530.00, $2,530.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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