CLK4

Gene Symbol CLK4
Entrez Gene 57396
Alt Symbol -
Species Human
Gene Type protein-coding
Description CDC-like kinase 4
Other Description dual specificity protein kinase CLK4|protein serine threonine kinase Clk4
Swissprots Q9HAZ1
Accessions EAW53831 EAW53832 Q9HAZ1 AF294429 AAG10074 AK294921 BAH11925 AK304614 BAH14226 AK308578 AK308674 AK308879 AK309215 AK310427 AK311485 BC015942 BC034633 AAH34633 BC046211 BC063116 BC065732 AAH65732 BC136261 AAI36262 BC143538 BC143547 AAI43548 BC151233 BX647323 CB127989 CR749504 CAH18325 XM_005265947 XP_005266004 XM_005265948 XP_005266005 XM_005265949 XP_005266006 XM_006714895 XP_006714958 XM_006714896 XP_006714959 XM_011534601 XP_011532903 XM_011534602 XP_011532904 XM_011534603 XP_011532905 XR_427807 NM_020666 NP_065717
Function Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates SRSF1 and SRSF3. Required for the regulation of alternative splicing of MAPT/TAU. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells. {ECO:0000269|PubMed:11170754, ECO:0000269|PubMed:19168442}.
Subcellular Location Nucleus {ECO:0000250}.
Tissue Specificity Expressed in liver, kidney, heart, muscle, brain and endothelial cells. {ECO:0000269|PubMed:11170754, ECO:0000269|PubMed:19168442}.

CLK4 CRISPR/Cas9 KO Plasmid (h) - sc-404084 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLK4 HDR Plasmid (h) - sc-404084-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLK4 Double Nickase Plasmid (h) - sc-404084-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLK4 Double Nickase Plasmid (h2) - sc-404084-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLK4 CRISPR Activation Plasmid (h) - sc-404084-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLK4 CRISPR Activation Plasmid (h2) - sc-404084-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLK4 Lentiviral Activation Particles (h) - sc-404084-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLK4 Lentiviral Activation Particles (h2) - sc-404084-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLK4 siRNA (h) - sc-105214 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CLK4 shRNA Plasmid (h) - sc-105214-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CLK4 shRNA (h) Lentiviral Particles - sc-105214-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CLK4 RNAi - H00057396-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU027271 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® siRNA - SIHK0468 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK0467 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK0469 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN6243 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6243 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CLK4 siRNA (Human) - CRJ1428 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CLK4 - MBS8228628 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Clk4 (NM_020666.2) - SHH265445 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CLK4(NM_020666.2) - SHG183295 from Creative biogene

Category siRNA
Species Reactivities Human

CLK4 shRNA Plasmid (Human) - CHJ1428 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CLK4 miRNA 3'UTR clone - MiUTR1H-02229 from Creative biogene

Species Reactivities Human
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