HDAC5

Gene Symbol	HDAC5
Entrez Gene	10014
Alt Symbol	HD5, NY-CO-9
Species	Human
Gene Type	protein-coding
Description	histone deacetylase 5
Other Description	antigen NY-CO-9
Swissprots	C9JFV9 Q9UQL6 Q96DY4 O60340 O60528
Accessions	DAA00017 EAW51633 EAW51634 Q9UQL6 AB011172 BAA25526 AB177853 BAD66831 AF039691 AAC18040 AF132608 AAD29047 AK027734 BAB55329 AK075095 AK093150 AK294760 BAG57895 BC011260 BC013140 AAH13140 BC038423 BC041914 BC051824 AAH51824 BM564861 BM998071 CN290533 XM_005256904 XP_005256961 XM_005256905 XP_005256962 XM_005256906 XP_005256963 XM_005256907 XP_005256964 XM_011524149 XP_011522451 XM_011524150 XP_011522452 XM_011524151 XP_011522453 XR_934338 NM_001015053 NP_001015053 NM_005474 NP_005465 NM_139205
Function	Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. {ECO:0000269|PubMed:24413532}.
Subcellular Location	Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm. In muscle cells, it shuttles into the cytoplasm during myocyte differentiation. The export to cytoplasm depends on the interaction with a 14-3-3 chaperone protein and is due to its phosphorylation at Ser-259 and Ser-498 by AMPK, CaMK1 and SIK1.
Tissue Specificity	Ubiquitous.
Top Pathways	Viral carcinogenesis, Epstein-Barr virus infection, Alcoholism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse/Human Phospho-HDAC5 (Ser498) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1524 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.313-20 ng/ml

Human HDAC5 ELISA Kit (Sandwich ELISA) - LS-F9475 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.113 ng/ml Range 0.313-20 ng/ml

Human Histone Deacetylase 5 ELISA Kit - abx151818 from Abbexa Category ELISA Kit Sensitivity 0.113 ng/ml Range 0.313 ng/ml - 20 ng/ml

Histone Deacetylase 5 (HDAC5), Human, ELISA Kit - SEE905Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.113ng/mL Range 0.312-20ng/mL

HDAC5 Colorimetric Cell-Based ELISA Kit - CB5323 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

HDAC5 (Phospho-Ser259) Colorimetric Cell-Based ELISA Kit - CBP1123 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

HDAC5 (Phospho-Ser498) Colorimetric Cell-Based ELISA Kit - CBP1570 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

Histone Deacetylase 5, ELISA Kit - MBS095593 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1ng/ml. Range 0.625ng/ml-20ng/ml.

Histone Deacetylase 5, ELISA Kit - MBS078222 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Deacetylase 5, ELISA Kit - MBS073916 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Deacetylase 5, ELISA Kit - MBS060864 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Deacetylase 5, ELISA Kit - MBS061638 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Deacetylase 5, ELISA Kit - MBS078583 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Deacetylase 5, ELISA Kit - MBS077564 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Histone Deacetylase 5 (HDAC5) - SEE905Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.113ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for Histone Deacetylase 5 (HDAC5) - SEE905Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.113ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human Histone Deacetylase 5 (HDAC5) ELISA Kit - EKU04818 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.113 ng/mL Range 0.312-20 ng/mL

HDAC5 ELISA Kit - DEIA-XYA781 from Creative Diagnostics Category ELISA Kit

HDAC5 (Phospho-Ser259) ELISA Kit - DEIA-XYA782 from Creative Diagnostics Category ELISA Kit

HDAC5 (Phospho-Ser498) ELISA Kit - DEIA-XYA783 from Creative Diagnostics Category ELISA Kit

Human HDAC5 ELISA Kit - E018804 from Biobool Category ELISA Kit Sensitivity Typically less than 0.113ng/mL.

HDAC5 ELISA Kit (Human) (OKCD01848) - OKCD01848 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity < 0.113 ng/mL Range 0.312 - 20 ng/mL

Histone Deacetylase 5 (HDAC5), ELISA Kit - MBS456180 from MyBioSource Category ELISA Kit Prices $415.00, $550.00, $2,425.00, $4,710.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.113ng/mL Range 0.312-20ng/mL

Histone Deacetylase 5 (HDAC5), ELISA Kit - MBS9381200 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

HDAC5 Colorimetric Cell-Based ELISA Kit - EKA50276 from Biomatik Category ELISA Kit Prices $399.00 Sizes 96 tests Sensitivity At least 5000 cells/well Range Qualitative

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