DDHD2

Gene Symbol DDHD2
Entrez Gene 23259
Alt Symbol SAMWD1, SPG54, iPLA(1)gamma
Species Human
Gene Type protein-coding
Description DDHD domain containing 2
Other Description PA-PLA1 like|SAM, WWE and DDHD domain-containing protein 1|intracellular phospholipase A1gamma|phospholipase DDHD2|sec23p-interacting protein p125-like phosphatidic acid-preferring phospholipase A1
Swissprots B3KXB5 O94830 Q9H8X7 B3KWV2
Accessions EAW63323 EAW63324 O94830 AB018268 BAA34445 AK023218 BAB14470 AK026961 AK056525 BAG51738 AK094951 AK125904 BAG54264 AK127040 BAG54427 AK299875 BAG61725 BC010504 AAH10504 BI789108 BM510691 DA333302 DA412370 XM_005273454 XP_005273511 XM_005273455 XP_005273512 XM_005273456 XP_005273513 XM_005273457 XP_005273514 XM_011544455 XP_011542757 XM_011544456 XP_011542758 XR_247123 XR_949383 XR_949384 XR_949385 XR_949386 XR_949387 NM_001164232 NP_001157704 NM_001164234 NP_001157706 NM_015214 NP_056029
Function Phospholipase that hydrolyzes preferentially phosphatidic acid, including 1,2-dioleoyl-sn-phosphatidic acid, and phosphatidylethanolamine. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4- phosphate (PI(4)P), phosphatidylinositol 5-phosphate (PI(5)P) and possibly phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2). May be involved in the maintenance of the endoplasmic reticulum and/or Golgi structures. May regulate the transport between Golgi apparatus and plasma membrane. {ECO:0000269|PubMed:11788596, ECO:0000269|PubMed:20932832, ECO:0000269|PubMed:22922100}.
Subcellular Location Cytoplasm, cytosol. Endoplasmic reticulum- Golgi intermediate compartment. Golgi apparatus, cis-Golgi network. Note=Cycles between the Golgi apparatus and the cytosol. DDHD2 recruitment to the Golgi/endoplasmic reticulum-Golgi intermediate compartment (ERGIC) is regulated by the levels of phosphoinositides, including PI(4)P.
Tissue Specificity Widely expressed (at protein level). {ECO:0000269|PubMed:11788596}.

DDHD2 (N-14) - sc-87679 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-DDHD2 antibody - ab103965 from Abcam

Prices $359.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-DDHD2 antibody (ab103965) at 1/100 dilution + K562 cell line lysates at 35 µg

Anti-DDHD2 Antibody - LS-C307201 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-DDHD2 Antibody (aa179-228) - LS-C111617 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
DDHD2 antibody LS-C111617 Western blot of THP-1 cell lysate.

DDHD2 Antibody - 21400002 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

DDHD2 Antibody - NBP1-82965 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: DDHD2 Antibody [NBP1-82965] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue. Lane 6: Human tonsil tissue

DDHD2 Antibody - NBP1-82966 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: DDHD2 Antibody [NBP1-82966] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251MG sp<br/>Lane 4: Human plasma (IgG/HSA depleted)<br/>Lane 5: Human liver tissue<br/>Lane 6: Human tonsil tissue

DDHD2 Antibody - H00023259-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: DDHD2 Antibody [H00023259-B01] - analysis of DDHD2 expression in transfected 293T cell line by DDHD2 MaxPab polyclonal antibody. Lane 1: DDHD2 transfected lysate (81.00 KDa). Lane 2: Non-transfected lysate.

Anti-DDHD2 antibody produced in rabbit - HPA023147 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-DDHD2: <B>Cat. No. HPA023147</B>: Immunohistochemical staining of human small intestine shows strong positivity in glandular cells.

Anti-DDHD2 antibody produced in mouse - SAB1407193 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-DDHD2: <B>Cat. No. SAB1407193</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~81 kDa using DDHD2 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-DDHD2 antibody produced in rabbit - HPA023150 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-DDHD2: <B>Cat. No. HPA023150</B>: Immunohistochemical staining of human esophagus shows strong cytoplasmic positivity in squamous epithelial cells.

Anti-DDHD2, (N-terminal) antibody produced in rabbit - SAB2105963 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-DDHD2 (N-Terminal): <B>Cat. No. SAB2105963</B>: DDHD2 in THP-1 cell lysates with DDHD2 antibody at 1.0 μg/mL.

Anti-DDHD2 antibody produced in rabbit - HPA023143 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-DDHD2: <B>Cat. No. HPA023143</B>: Immunohistochemical staining of human skeletal muscle shows cytoplasmic positivity in myocytes.

DDHD2 antibody - N-terminal region (ARP55202_P050) - ARP55202_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DDHD2 antibody, N-term - GTX45318 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal
Anti-DDHD2 antibody, N-term used in Western blot. GTX45318

DDHD2 antibody - 70R-4082 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

DDHD2 antibody - 25203-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent analysis of HEK-293 cells using 25203-1-AP( DDHD2 Antibody) at dilution of 1:25 and Alexa Fluor 594-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

DDHD2 antibody - H00023259-B01 from Acris Antibodies

Prices $360.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot analysis of DDHD2 expression in transfected 293T cell line (H00023259-T01) by DDHD2 MaxPab polyclonal antibody. Lane 1: DDHD2 transfected lysate(81.00 KDa). Lane 2: Non-transfected lysate.

DDHD2 antibody - H00023259-B01P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot analysis of DDHD2 expression in transfected 293T cell line (H00023259-T01) by DDHD2 MaxPab polyclonal antibody. Lane 1: DDHD2 transfected lysate(81.00 KDa). Lane 2: Non-transfected lysate.

DDHD2 antibody - 25203-1-AP from Proteintech Group

Prices $279.00
Sizes con: 58 μg/150μl
Host Rabbit
Clonality Polyclonal
rat brain tissue were subjected to SDS PAGE followed by western blot with 25203-1-AP( DDHD2 Antibody) at dilution of 1:2000

DDHD2 Antibody - GWB-MT738I from Genway Biotech

Prices $404.00
Sizes 50 µg
Clonality Polyclonal

Anti-DDHD2 monoclonal antibody - DCABH-15143 from Creative Diagnostics

Host Rabbit
Clonality Monoclonal

DDHD2, Polyclonal Antibody - MBS6003102 from MyBioSource

Prices $580.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

DDHD2 antibody - TA590518 from Acris Antibodies

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: DDHD2 Antibody - Samples: Lane 1, Marker: 250, 130, 95, 72, 55, 36, 28, 17, 11 Lane 2, RT-4 Lane 3, U-251MG sp Lane 4, Human Plasma Lane 5, Liver Lane 6, Tonsil , Target weight: 81, 44 (splice variants) Validation score: 2 Validation description: Supportive - Band of predicted size in kDa (+/-20%) with additional bands present.
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