DDHD2

Gene Symbol DDHD2
Entrez Gene 23259
Alt Symbol SAMWD1, SPG54, iPLA(1)gamma
Species Human
Gene Type protein-coding
Description DDHD domain containing 2
Other Description PA-PLA1 like|SAM, WWE and DDHD domain-containing protein 1|intracellular phospholipase A1gamma|phospholipase DDHD2|sec23p-interacting protein p125-like phosphatidic acid-preferring phospholipase A1
Swissprots B3KXB5 O94830 Q9H8X7 B3KWV2
Accessions EAW63323 EAW63324 O94830 AB018268 BAA34445 AK023218 BAB14470 AK026961 AK056525 BAG51738 AK094951 AK125904 BAG54264 AK127040 BAG54427 AK299875 BAG61725 BC010504 AAH10504 BI789108 BM510691 DA333302 DA412370 XM_005273454 XP_005273511 XM_005273455 XP_005273512 XM_005273456 XP_005273513 XM_005273457 XP_005273514 XM_011544455 XP_011542757 XM_011544456 XP_011542758 XR_247123 XR_949383 XR_949384 XR_949385 XR_949386 XR_949387 NM_001164232 NP_001157704 NM_001164234 NP_001157706 NM_015214 NP_056029
Function Phospholipase that hydrolyzes preferentially phosphatidic acid, including 1,2-dioleoyl-sn-phosphatidic acid, and phosphatidylethanolamine. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4- phosphate (PI(4)P), phosphatidylinositol 5-phosphate (PI(5)P) and possibly phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2). May be involved in the maintenance of the endoplasmic reticulum and/or Golgi structures. May regulate the transport between Golgi apparatus and plasma membrane. {ECO:0000269|PubMed:11788596, ECO:0000269|PubMed:20932832, ECO:0000269|PubMed:22922100}.
Subcellular Location Cytoplasm, cytosol. Endoplasmic reticulum- Golgi intermediate compartment. Golgi apparatus, cis-Golgi network. Note=Cycles between the Golgi apparatus and the cytosol. DDHD2 recruitment to the Golgi/endoplasmic reticulum-Golgi intermediate compartment (ERGIC) is regulated by the levels of phosphoinositides, including PI(4)P.
Tissue Specificity Widely expressed (at protein level). {ECO:0000269|PubMed:11788596}.

DDHD2 CRISPR/Cas9 KO Plasmid (h) - sc-411700 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DDHD2 HDR Plasmid (h) - sc-411700-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DDHD2 Double Nickase Plasmid (h) - sc-411700-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DDHD2 Double Nickase Plasmid (h2) - sc-411700-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DDHD2 CRISPR Activation Plasmid (h) - sc-411700-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DDHD2 CRISPR Activation Plasmid (h2) - sc-411700-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DDHD2 Lentiviral Activation Particles (h) - sc-411700-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DDHD2 Lentiviral Activation Particles (h2) - sc-411700-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DDHD2 siRNA (h) - sc-77719 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DDHD2 shRNA Plasmid (h) - sc-77719-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DDHD2 shRNA (h) Lentiviral Particles - sc-77719-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DDHD2 RNAi - H00023259-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU028371 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7022 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7022 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06527 from Sigma-Aldrich

Category miRNA

DDHD2 siRNA (Human) - CRH8131 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DDHD2 - MBS8221368 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human DDHD2 (NM_015214.2) - SHH275617 from Creative biogene

Category siRNA
Species Reactivities Human

Human DDHD2 siRNA - orb268633 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DDHD2 shRNA Plasmid (Human) - CHH8131 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DDHD2 miRNA 3'UTR clone - MiUTR3H-14612 from Creative biogene

Species Reactivities Human
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