DDHD2

Gene Symbol	DDHD2
Entrez Gene	23259
Alt Symbol	SAMWD1, SPG54, iPLA(1)gamma
Species	Human
Gene Type	protein-coding
Description	DDHD domain containing 2
Other Description	PA-PLA1 like|SAM, WWE and DDHD domain-containing protein 1|intracellular phospholipase A1gamma|phospholipase DDHD2|sec23p-interacting protein p125-like phosphatidic acid-preferring phospholipase A1
Swissprots	B3KXB5 O94830 Q9H8X7 B3KWV2
Accessions	EAW63323 EAW63324 O94830 AB018268 BAA34445 AK023218 BAB14470 AK026961 AK056525 BAG51738 AK094951 AK125904 BAG54264 AK127040 BAG54427 AK299875 BAG61725 BC010504 AAH10504 BI789108 BM510691 DA333302 DA412370 XM_005273454 XP_005273511 XM_005273455 XP_005273512 XM_005273456 XP_005273513 XM_005273457 XP_005273514 XM_011544455 XP_011542757 XM_011544456 XP_011542758 XR_247123 XR_949383 XR_949384 XR_949385 XR_949386 XR_949387 NM_001164232 NP_001157704 NM_001164234 NP_001157706 NM_015214 NP_056029
Function	Phospholipase that hydrolyzes preferentially phosphatidic acid, including 1,2-dioleoyl-sn-phosphatidic acid, and phosphatidylethanolamine. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4- phosphate (PI(4)P), phosphatidylinositol 5-phosphate (PI(5)P) and possibly phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2). May be involved in the maintenance of the endoplasmic reticulum and/or Golgi structures. May regulate the transport between Golgi apparatus and plasma membrane. {ECO:0000269|PubMed:11788596, ECO:0000269|PubMed:20932832, ECO:0000269|PubMed:22922100}.
Subcellular Location	Cytoplasm, cytosol. Endoplasmic reticulum- Golgi intermediate compartment. Golgi apparatus, cis-Golgi network. Note=Cycles between the Golgi apparatus and the cytosol. DDHD2 recruitment to the Golgi/endoplasmic reticulum-Golgi intermediate compartment (ERGIC) is regulated by the levels of phosphoinositides, including PI(4)P.
Tissue Specificity	Widely expressed (at protein level). {ECO:0000269|PubMed:11788596}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DDHD2 full length protein - ab161583 from Abcam Category Protein Source Wheat germ Species Human

DDHD2 Antibody Blocking Peptide - LS-E19930 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human DDHD2 Protein - H00023259-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

DDHD2 Blocking Peptide - 33R-1971 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

DDHD2 - H00023259-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

DDHD2 - H00023259-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

DDHD2 fusion protein - Ag18373 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human DDHD2, GST-tagged - DDHD2-11880H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Phospholipase DDHD2(DDHD2) - CSB-YP006586HU CSB-EP006586HU CSB-BP006586HU CSB-MP006586HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

DDHD2 (transcript variant 2) - TP328552 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Phospholipase DDHD2 (DDHD2), Recombinant Protein - MBS1176963 from MyBioSource Category Protein Prices $1,520.00, $1,520.00, $1,745.00, $1,745.00, $2,600.00, $2,600.00, $3,045.00, $3,045.00 Sizes 50 µg (Baculovirus), 500 µg (E-Coli), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

DDHD2 Recombinant Protein Antigen - NBP1-82967PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

DDHD2 Protein - NBP1-82966PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

DDHD2 Recombinant Protein Antigen - NBP1-82965PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

DDHD2-Antibody-N-term-Blocking-Peptide - BP5025a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DDHD2 Peptide, Human - M34GP04120H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Human DDHD2 Protein, His-tagged - DDHD2-226H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human DDHD2 Protein, MYC/DDK-tagged - DDHD2-230H from Creative Biomart Category Protein Source HEK293 Species Human

Recombinant Human DDHD2 Protein, GST-tagged - DDHD2-2439H from Creative Biomart Category Protein Source Wheat Germ Species Human

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