TSG101

Gene Symbol	TSG101
Entrez Gene	7251
Alt Symbol	TSG10, VPS23
Species	Human
Gene Type	protein-coding
Description	tumor susceptibility 101
Other Description	ESCRT-I complex subunit TSG101|tumor susceptibility gene 10|tumor susceptibility gene 101|tumor susceptibility gene 101 protein|tumor susceptibility protein
Swissprots	Q9BUM5 Q99816
Accessions	EAW68381 EAW68382 EAW68383 EAW68384 EAW68385 EAW68386 Q99816 AK130787 AU138453 AY207473 AAO59169 AY207474 AAO59170 BC002487 AAH02487 BP347883 CB528488 DQ892792 ABM83718 DQ896039 ABM87038 U82130 AAC52083 XM_005253108 XP_005253165 NM_006292 NP_006283
Function	Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses. {ECO:0000269|PubMed:11916981, ECO:0000269|PubMed:17556548, ECO:0000269|PubMed:17853893, ECO:0000269|PubMed:21070952, ECO:0000269|PubMed:21757351}.
Subcellular Location	Cytoplasm. Membrane; Peripheral membrane protein. Nucleus. Late endosome membrane; Peripheral membrane protein. Note=Mainly cytoplasmic. Membrane-associated when active and soluble when inactive. Depending on the stage of the cell cycle, detected in the nucleus. Colocalized with CEP55 in the midbody during cytokinesis.
Tissue Specificity	Heart, brain, placenta, lung, liver, skeletal, kidney and pancreas.
Top Pathways	Endocytosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rabbit anti-TSG101 Antibody, Affinity Purified - PLA0283 from Sigma-Aldrich Prices $323.50 Sizes 100 µl

Human TSG101 ELISA Kit (Sandwich ELISA) - LS-F8581 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.313 ng/ml Range 0.313-20 ng/ml

Tumor Susceptibility Gene 101 (TSG101), Human, ELISA Kit - SEC814Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.105ng/mL Range 0.312-20ng/mL

Tumor susceptibility gene 101 protein (TSG101), Human, ELISA Kit - CSB-EL025125HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

TSG101 (Human) IP-WB Antibody Pair - H00007251-PW2 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

tumor susceptibility gene 101, ELISA Kit - MBS938622 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human TSG101 is typically less than 5.86 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 23.44 pg/ml-1500 pg/ml.

Tumor Susceptibility Gene 101 (TSG101), ELISA Kit - MBS2023399 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.128ng/mL. Range 0.313-20ng/mL

ELISA Kit for Tumor Susceptibility Gene 101 (TSG101) - SEC814Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.128ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human Tumor susceptibility gene 101 protein(TSG101) ELISA kit - CSB-EL025125HU from Cusabio Category ELISA Kit Sensitivity 5.86 pg/ml Range 23.44 pg/ml-1500 pg/ml

ELISA Kit for Tumor Susceptibility Gene 101 (TSG101) - SEC814Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.128ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human TSG101 ELISA Kit - abx153403 from Abbexa Category ELISA Kit Sensitivity 0.105 ng/ml Range 0.313 ng/ml - 20 ng/ml

Tumor Susceptibility Gene 101 (TSG101), Human, ELISA Kit - DL-TSG101-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.312-20 ng/mL

Human TSG101 ELISA Kit - abx572890 from Abbexa Category ELISA Kit Sensitivity 0.105 ng/ml Range 0.313 ng/ml - 20 ng/ml

Human TSG101 ELISA Kit - E040057 from Biobool Category ELISA Kit

TSG101 ELISA Kit (Human) (OKCD01703) - OKCD01703 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity < 0.114 ng/mL Range 0.312 - 20 ng/mL

anti-TSG101 antibody - ARG55805 from Arigo Biolaboratories Category ELISA Kit

Human Tumor susceptibility gene 101 protein (TSG101) ELISA Kit - AE13155HU from ARP American Research Products Category ELISA Kit Prices $549.00 Sizes 96 t Sensitivity 0.114 ng/mL Range 0.312-20 ng/mL

Tumor Susceptibility Gene 101 (TSG101), ELISA Kit - MBS450297 from MyBioSource Category ELISA Kit Prices $415.00, $550.00, $2,425.00, $4,710.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.105ng/mL Range 0.312-20ng/mL

Tumor Susceptibility Gene 101 (TSG101), ELISA Kit - MBS9376438 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

TSG101 ELISA Kit (Human) (OKCA02151) - OKCA02151 from Aviva Systems Biology Category ELISA Kit Sensitivity 5.86 pg/mL Range 23.44 pg/mL-1,500 pg/mL

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