Gene Symbol | PDCL3 |
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Entrez Gene | 79031 |
Alt Symbol | HTPHLP, PHLP2A, PHLP3, VIAF, VIAF1 |
Species | Human |
Gene Type | protein-coding |
Description | phosducin-like 3 |
Other Description | IAP-associated factor VIAF1|VIAF-1|phPL3|phosducin-like protein 3|viral IAP-associated factor 1 |
Swissprots | Q9H2J4 B2RA00 Q53S68 |
Accessions | AAX93227 EAX01837 EAX01838 Q9H2J4 AF110511 AAG21887 AF267853 AAG44722 AI741007 AK300827 BAH13356 AK313985 BAG36697 BC001021 AAH01021 BG819099 BI820064 HQ448695 ADQ33173 NM_024065 NP_076970 |
Function | Acts as a chaperone for the angiogenic VEGF receptor KDR/VEGFR2, controlling its abundance and inhibiting its ubiquitination and degradation. Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination. {ECO:0000269|PubMed:15371430, ECO:0000269|PubMed:23792958}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:15371430}. |
Tissue Specificity | Expressed in all tissues examined including spleen, thymus, prostate, testis, ovary, small intestine and colon. {ECO:0000269|PubMed:15371430}. |
PDCL3 (F-12) - sc-107923 from Santa Cruz Biotechnology
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PDCL3 (T-12) - sc-107925 from Santa Cruz Biotechnology
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PDCL3 (J-16) - sc-100806 from Santa Cruz Biotechnology
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Anti-PDCL3 antibody - ab57708 from Abcam
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Anti-PDCL3 antibody - C-terminal - ab191612 from Abcam
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Anti-PDCL3 antibody - N-terminal - ab171662 from Abcam
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Anti-PDCL3 Antibody (aa39-68, AP) - LS-C265856 from LifeSpan Bioscience
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Anti-PDCL3 Antibody (aa39-68, APC) - LS-C265858 from LifeSpan Bioscience
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Anti-PDCL3 Antibody (aa39-68, Biotin) - LS-C265859 from LifeSpan Bioscience
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Anti-PDCL3 Antibody (aa39-68, FITC) - LS-C265860 from LifeSpan Bioscience
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Anti-PDCL3 Antibody (aa39-68, Azide-free, HRP) - LS-C265861 from LifeSpan Bioscience
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Anti-PDCL3 Antibody (aa38-68) - LS-C323881 from LifeSpan Bioscience
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Anti-PDCL3 Antibody (aa39-68, PE) - LS-C265862 from LifeSpan Bioscience
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Anti-PDCL3 Antibody (aa39-68) - LS-C158557 from LifeSpan Bioscience
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Anti-PDCL3 Antibody - LS-C178495 from LifeSpan Bioscience
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Anti-PDCL3 Antibody (C-Terminus) IHC-plus⢠- LS-B12151 from LifeSpan Bioscience
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PDCL3 Antibody - NBP1-80626 from Novus Biologicals
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PDCL3 Antibody - NBP1-80627 from Novus Biologicals
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PDCL3 Antibody (1F10) - H00079031-M01 from Novus Biologicals
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PDCL3 Antibody (1F10) - H00079031-M01A from Novus Biologicals
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Anti-PDCL3 antibody produced in rabbit - HPA027094 from Sigma-Aldrich
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Monoclonal Anti-PDCL3 antibody produced in mouse - WH0079031M1 from Sigma-Aldrich
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PDCL3-Antibody-N-term - AP13347a from Abgent, a WuXi AppTec company
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PDCL3-Antibody-monoclonal-M01 - AT3249a from Abgent, a WuXi AppTec company
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PDCL3 Antibody - N-terminal region (OAAB09661) - OAAB09661 from Aviva Systems Biology
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