Gene Symbol | PDCL3 |
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Entrez Gene | 79031 |
Alt Symbol | HTPHLP, PHLP2A, PHLP3, VIAF, VIAF1 |
Species | Human |
Gene Type | protein-coding |
Description | phosducin-like 3 |
Other Description | IAP-associated factor VIAF1|VIAF-1|phPL3|phosducin-like protein 3|viral IAP-associated factor 1 |
Swissprots | Q9H2J4 B2RA00 Q53S68 |
Accessions | AAX93227 EAX01837 EAX01838 Q9H2J4 AF110511 AAG21887 AF267853 AAG44722 AI741007 AK300827 BAH13356 AK313985 BAG36697 BC001021 AAH01021 BG819099 BI820064 HQ448695 ADQ33173 NM_024065 NP_076970 |
Function | Acts as a chaperone for the angiogenic VEGF receptor KDR/VEGFR2, controlling its abundance and inhibiting its ubiquitination and degradation. Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination. {ECO:0000269|PubMed:15371430, ECO:0000269|PubMed:23792958}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:15371430}. |
Tissue Specificity | Expressed in all tissues examined including spleen, thymus, prostate, testis, ovary, small intestine and colon. {ECO:0000269|PubMed:15371430}. |
Human PDCL3 full length protein - ab123207 from Abcam
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PDCL3 Antibody Blocking Peptide - LS-E2375 from LifeSpan Bioscience
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PDCL3 Recombinant Protein - H00079031-P01 from Novus Biologicals
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Recombinant Human PDCL3 Protein - NBP1-78882 from Novus Biologicals
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PDCL3-Antibody-N-term-Blocking-peptide - BP13347a from Abgent, a WuXi AppTec company
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Human PDCL3 protein - orb169000 from Biorbyt
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PDCL3 (1-239, His-tag) - AR50208PU-N from Acris Antibodies
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PDCL3 (1-239, His-tag) - AR50208PU-S from Acris Antibodies
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PDCL3 - H00079031-P01-10 from Acris Antibodies
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PDCL3 - H00079031-P01-25 from Acris Antibodies
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Phosducin-Like 3, Human Recombinant - 228-12850-1 from RayBiotech
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Recombinant Phosducin-Like 3 Human - 228-12850-2 from RayBiotech
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Recombinant Phosducin-Like 3 Human - 228-12850-3 from RayBiotech
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PDCL3, 1-239aa, Human, His tag, E.coli - 01-P1383 from ARP American Research Products
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PDCL3 Peptide - 7889P from ProSci
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PDCL3 fusion protein - Ag7063 from Proteintech Group
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PDCL3 fusion protein - Ag6983 from Proteintech Group
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Recombinant Human PDCL3 Protein - BP002913-PRO-1028 from Syd Labs
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PDCL3, 1-239aa, Recombinant Protein - GWB-P0655E from Genway Biotech
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Recombinant Human PDCL3, His-tagged - PDCL3-1598H from Creative Biomart
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Recombinant Human Phosducin-Like 3, His-tagged - PDCL3-1383H from Creative Biomart
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PDCL3 1-239aa - CMB-1216 from Reagent Proteins
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Recombinant Human Phosducin-like protein 3(PDCL3) - CSB-YP872479HU CSB-EP872479HU CSB-BP872479HU CSB-MP872479HU from Cusabio
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PDCL3, 1-239aa, Human, His tag, E.coli - ATGP1383 from ATGen
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Phosducin-Like 3 Protein (Recombinant) - abx262102 from Abbexa
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