SERPINA3

Gene Symbol	SERPINA3
Entrez Gene	12
Alt Symbol	AACT, ACT, GIG24, GIG25
Species	Human
Gene Type	protein-coding
Description	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
Other Description	alpha-1-antichymotrypsin|cell growth-inhibiting gene 24/25 protein|growth-inhibiting protein 24|growth-inhibiting protein 25|serine (or cysteine) proteinase inhibitor, clade A, member 3|serpin A3
Swissprots	Q6LBY8 P01011 Q9UC47 Q6LDT7 Q59GP9 Q9UNU9 B3KVQ7 Q6NSC9 Q13703 Q96DW8 Q8N177 Q2TU88 Q2TU87
Accessions	CAA25459 CAA48671 CAI95958 EAW81587 EAW81588 EAW81589 EAW81590 P01011 AB209060 BAD92297 AF089747 AAD08810 AK093049 BAG52641 AK096120 AK123091 BAG53869 AK308565 AY513275 AAT08028 AY513276 AAT08029 BC003559 AAH03559 BC010530 AAH10530 BC013189 AAH13189 BC034554 AAH34554 BC070265 AAH70265 BG565041 CB111903 HQ448280 ADQ32760 J05176 AAA51560 K01500 AAA51543 M18906 AAA51559 M22533 NM_001085 NP_001076
Function	Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2. {ECO:0000269|PubMed:2404007}.
Subcellular Location	Secreted.
Tissue Specificity	Plasma. Synthesized in the liver. Like the related alpha-1-antitrypsin, its concentration increases in the acute phase of inflammation or infection. Found in the amyloid plaques from the hippocampus of Alzheimer disease brains. {ECO:0000269|PubMed:3257719, ECO:0000269|PubMed:9880565}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SerpinA3 gene - orb90896 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

Human-SERPINA3-cDNA-Clone - DC01325 from Abgent, a WuXi AppTec company Prices $571.05 Sizes 10 µg Species Human Accession BC003559

SERPINA3 - MBS1277501 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC003559

SERPINA3 - MBS1269148 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC034554

Human SerpinA3 Gene cDNA clone plasmid - HG10307-M from Sino Biological Species Human

Human SerpinA3 Gene ORF cDNA clone expression plasmid, N-His tag - HG10307-NH from Sino Biological Species Human

Human SerpinA3 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10307-CM from Sino Biological Species Human

Human SerpinA3 Gene cDNA Clone (full-length ORF Clone) expression ready, untagged - HG10307-M-N from Sino Biological Species Human Accession NM_001085.4

Human SerpinA3 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10307-ACG from Sino Biological Species Human

Human SerpinA3 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10307-ACR from Sino Biological Species Human

Human SerpinA3 Gene ORF cDNA clone expression plasmid - HG10307-UT from Sino Biological Species Human

Human SerpinA3 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10307-CY from Sino Biological Species Human

Human SerpinA3 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10307-NF from Sino Biological Species Human

Human SerpinA3 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10307-NM from Sino Biological Species Human

Human SerpinA3 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10307-CF from Sino Biological Species Human

Human SerpinA3 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10307-NY from Sino Biological Species Human

Human SerpinA3 Gene ORF cDNA clone expression plasmid, C-His tag - HG10307-CH from Sino Biological Species Human

Human SerpinA3 ORF clone(NM_001085.4) - CDCL186119 from Creative biogene Species Human

Human SERPINA3 ORF Clone (BC003559) - CDCS407372 from Creative biogene Species Human Accession P01011

Human SERPINA3 ORF Clone (BC034554) - CDCS407373 from Creative biogene Species Human Accession P01011

Human SERPINA3 cDNA Clone(NM_001085.4) - CDFH017257 from Creative biogene Species Human

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