SERPINA3

Gene Symbol	SERPINA3
Entrez Gene	12
Alt Symbol	AACT, ACT, GIG24, GIG25
Species	Human
Gene Type	protein-coding
Description	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
Other Description	alpha-1-antichymotrypsin|cell growth-inhibiting gene 24/25 protein|growth-inhibiting protein 24|growth-inhibiting protein 25|serine (or cysteine) proteinase inhibitor, clade A, member 3|serpin A3
Swissprots	Q6LBY8 P01011 Q9UC47 Q6LDT7 Q59GP9 Q9UNU9 B3KVQ7 Q6NSC9 Q13703 Q96DW8 Q8N177 Q2TU88 Q2TU87
Accessions	CAA25459 CAA48671 CAI95958 EAW81587 EAW81588 EAW81589 EAW81590 P01011 AB209060 BAD92297 AF089747 AAD08810 AK093049 BAG52641 AK096120 AK123091 BAG53869 AK308565 AY513275 AAT08028 AY513276 AAT08029 BC003559 AAH03559 BC010530 AAH10530 BC013189 AAH13189 BC034554 AAH34554 BC070265 AAH70265 BG565041 CB111903 HQ448280 ADQ32760 J05176 AAA51560 K01500 AAA51543 M18906 AAA51559 M22533 NM_001085 NP_001076
Function	Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2. {ECO:0000269|PubMed:2404007}.
Subcellular Location	Secreted.
Tissue Specificity	Plasma. Synthesized in the liver. Like the related alpha-1-antitrypsin, its concentration increases in the acute phase of inflammation or infection. Found in the amyloid plaques from the hippocampus of Alzheimer disease brains. {ECO:0000269|PubMed:3257719, ECO:0000269|PubMed:9880565}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human alpha 1 Antichymotrypsin full length protein - ab182695 from Abcam Category Protein Prices $449.00 Sizes 50 µg Source HEK 293 cells Species Human

Human alpha 1 Antichymotrypsin full length protein - ab80517 from Abcam Category Protein Prices $522.00 Sizes 1 mg Source Native Species Human

Human alpha 1 Antichymotrypsin full length protein - ab167777 from Abcam Category Protein Prices $285.00 Sizes 100 µg Source Native Species Human

Human alpha 1 Antichymotrypsin full length protein - ab152025 from Abcam Category Protein Prices $188.00 Sizes 10 µg Source HEK 293 cells Species Human

Human alpha 1 Antichymotrypsin full length protein - ab89363 from Abcam Category Protein Prices $188.00, $692.00 Sizes 100 µg, 500 µg Source E. coli Species Human

Serpin A3/alpha 1-Antichymotrypsin Recombinant Protein - H00000012-P02 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Serpin A3/alpha 1-Antichymotrypsin Recombinant Protein - H00000012-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Serpin A3/alpha 1-Antichymotrypsin Protein - NBP1-30283 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

Serpin A3/alpha 1-Antichymotrypsin Protein - P4947 from Novus Biologicals Category Protein Prices $449.00 Sizes 100 µg Species Human

SERPINA3-Antibody-Center-Blocking-Peptide - BP7314c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human Serpin A3, CF - 1295-PI-010 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Asn26-Ala423, with a C-terminal 10-His tag

Alpha 1-Antichymotrypsin Protein (OPMA04234) - OPMA04234 from Aviva Systems Biology Category Protein Prices $420.00 Sizes 1 mg Source Human Plasma

SERPINA3 Protein (OPPA01290) - OPPA01290 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 20 µg Source Human Serum

SERPINA3 Protein (OPPA02077) - OPPA02077 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human SerpinA3 His tag protein - orb83532 from Biorbyt Category Protein Prices $510.00, $748.00 Sizes 10 μg, 20 μg Source Human Species Human

Alpha 1-Antichymotrypsin protein - orb82113 from Biorbyt Category Protein Prices $544.00 Sizes 1 mg Source Sample obtained from Human. Species Human

Human Alpha-1 AntiChymotrypsin protein - orb81356 from Biorbyt Category Protein Prices $230.00, $442.00 Sizes 5 μg, 25 μg Source E.coli Species Human

Human SERPINA3 protein - orb78528 from Biorbyt Category Protein Prices $255.00, $391.00, $519.00 Sizes 10 μg, 50 μg, 100 μg Species Human

Human Alpha-1 AntiChymotrypsin protein - orb81357 from Biorbyt Category Protein Prices $170.00, $289.00, $502.00 Sizes 20 μg, 100 μg, 1 mg Source Human Serum

Human Serpin A3 protein - orb49644 from Biorbyt Category Protein Prices $408.00, $595.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Source HEK293

SERPINA3 peptide - orb218788 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

alpha 1 Antichymotrypsin protein - 30R-AA002 from Fitzgerald Category Protein Prices $1,695.00 Sizes 10 mg

Alpha 1 Antichymotrypsin protein - 30-1036 from Fitzgerald Category Protein Prices $225.00 Sizes 100 µg Species Human

alpha 1 Antichymotrypsin protein - 30-AC47 from Fitzgerald Category Protein Prices $445.00 Sizes 1 mg

Alpha 1 Antichymotrypsin protein (His tag) - 80R-1217 from Fitzgerald Category Protein Prices $220.00 Sizes 100 µg Source E.coli

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