RAB5A

Gene Symbol	RAB5A
Entrez Gene	5868
Alt Symbol	RAB5
Species	Human
Gene Type	protein-coding
Description	RAB5A, member RAS oncogene family
Other Description	RAS-associated protein RAB5A|ras-related protein Rab-5A
Swissprots	Q6FI44 P20339 B4DJA5
Accessions	EAW64301 EAW64302 EAW64303 P20339 AF464088 AAO15677 AF498936 AAM21084 AK295992 BAG58767 AK309287 AK312618 BAG35504 AM392797 CAL37675 AM393001 CAL37879 BC001267 AAH01267 BC018288 AAH18288 BJ991078 CR536492 CAG38731 DA972638 DC330362 DQ891790 ABM82716 DQ894972 ABM85898 M28215 AAA60245 X13903 CAA32103 NM_001292048 NP_001278977 NM_004162 NP_004153
Function	The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulation of filopodia extension. {ECO:0000269|PubMed:10818110, ECO:0000269|PubMed:14617813, ECO:0000269|PubMed:14978216, ECO:0000269|PubMed:15378032, ECO:0000269|PubMed:16410077}.
Subcellular Location	Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Early endosome membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. Melanosome. Cytoplasmic vesicle {ECO:0000250}. Cell projection, ruffle {ECO:0000250}. Membrane. Cytoplasm, cytosol. Note=Enriched in stage I melanosomes. Alternates between membrane-bound and cytosolic forms.
Top Pathways	Amyotrophic lateral sclerosis (ALS), Endocytosis, Vasopressin-regulated water reabsorption, Phagosome, Amoebiasis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse RAB5A / RAB5 ELISA Kit (Sandwich ELISA) - LS-F8466 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.056 ng/ml Range 0.313-20 ng/ml

Human RAB5A / RAB5 ELISA Kit (Sandwich ELISA) - LS-F8465 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.122 ng/ml Range 0.313-20 ng/ml

RAB5A, Member RAS Oncogene Family (RAB5A), Human, ELISA Kit - SEK305Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.122ng/mL Range 0.312-20ng/mL

RAB5A, Member RAS Oncogene Family (RAB5A), Human, CLIA Kit - SCK305Hu from ARP American Research Products Category CLIA Kit Prices $840.00 Sizes 96 t Sensitivity 0.02ng/mL Range 0.05-38ng/mL

RAB5A, member RAS oncogene family, ELISA Kit - MBS9340424 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

RAB5A, Member RAS Oncogene Family, ELISA Kit - MBS105245 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

RAB5A, Member RAS Oncogene Family, ELISA Kit - MBS050511 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

RAB5A, Member RAS Oncogene Family, ELISA Kit - MBS108414 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

RAB5A, Member RAS Oncogene Family, ELISA Kit - MBS080006 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

RAB5A, Member RAS Oncogene Family, ELISA Kit - MBS082364 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

RAB5A, Member RAS Oncogene Family, ELISA Kit - MBS062963 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

RAB5A, Member RAS Oncogene Family, ELISA Kit - MBS065782 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

RAB5A, Member RAS Oncogene Family (RAB5A), ELISA Kit - MBS2019647 from MyBioSource Category ELISA Kit Prices $385.00, $575.00, $785.00, $3,210.00, $5,825.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.062ng/mL. Range 0.156-10ng/mL

RAB5A, Member RAS Oncogene Family (RAB5A), ELISA Kit - MBS2023649 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human RAB5A is typically less than 0.122ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration. Range 0.312-20ng/mL

ELISA Kit for RAB5A, Member RAS Oncogene Family (RAB5A) - SEK305Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.122ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

CLIA Kit for RAB5A, Member RAS Oncogene Family (RAB5A) - SCK305Hu from Uscn Life Science Inc. Category CLIA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.02ng/mL. Range 0.052-38ng/mL The standard curve concentrations used for the CLIA’s were 38ng/mL, 12.667ng/mL, 4.222ng/mL, 1.407ng/mL, 0.469ng/mL, 0.156ng/mL, 0.052ng/mL

ELISA Kit for RAB5A, Member RAS Oncogene Family (RAB5A) - SEK305Mu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.062ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

CLIA Kit for RAB5A, Member RAS Oncogene Family (RAB5A) - SCK305Mu from Uscn Life Science Inc. Category CLIA Kit Sensitivity The minimum detectable dose of this kit is typically less than 6.37pg/mL. Range 13.72-10000pg/mL The standard curve concentrations used for the CLIA’s were 10000pg/mL, 3333.33pg/mL, 1111.11pg/mL, 370.37pg/mL, 123.46pg/mL, 41.15pg/mL, 13.72pg/mL

ELISA Kit for RAB5A, Member RAS Oncogene Family (RAB5A) - SEK305Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.122ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

CLIA Kit for RAB5A, Member RAS Oncogene Family (RAB5A) - SCK305Hu from Cloud-clone Category CLIA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.02ng/mL. Range 0.052-38ng/mL The standard curve concentrations used for the ELISA's were 38ng/mL, 12.67ng/mL, 4.22ng/mL, 1.41ng/mL, 0.469ng/mL, 0.156ng/mL, 0.052ng/mL

Human RAB5A, Member RAS Oncogene Family (RAB5A) ELISA Kit - EKU07002 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.122 ng/mL Range 0.312-20 ng/mL

CLIA Kit for RAB5A, Member RAS Oncogene Family (RAB5A) - CKU72495 from Biomatik Category CLIA Kit Prices $882.00 Sizes 96 t Sensitivity The limit of detection is typically less than 0.02ng/mL Range 0.594-38ng/mL The standard curve concentrations used for the ELISA’s were 38ng/mL, 19ng/mL, 9.5ng/mL, 4.75ng/mL, 2.375ng/mL, 1.188ng/mL, 0.594ng/mL

Human RAB5A ELISA Kit - abx152912 from Abbexa Category ELISA Kit Sensitivity 0.122 ng/ml Range 0.313 ng/ml - 20 ng/ml

Human RAB5A, Member RAS Oncogene Family CLIA Kit - abx190332 from Abbexa Category CLIA Kit Range 0.052 ng/ml - 38 ng/ml

RAB5A, Member RAS Oncogene Family (RAB5A), Human, ELISA Kit - DL-RAB5A-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.312-20 ng/mL

Search more