RAB5A

Gene Symbol RAB5A
Entrez Gene 5868
Alt Symbol RAB5
Species Human
Gene Type protein-coding
Description RAB5A, member RAS oncogene family
Other Description RAS-associated protein RAB5A|ras-related protein Rab-5A
Swissprots Q6FI44 P20339 B4DJA5
Accessions EAW64301 EAW64302 EAW64303 P20339 AF464088 AAO15677 AF498936 AAM21084 AK295992 BAG58767 AK309287 AK312618 BAG35504 AM392797 CAL37675 AM393001 CAL37879 BC001267 AAH01267 BC018288 AAH18288 BJ991078 CR536492 CAG38731 DA972638 DC330362 DQ891790 ABM82716 DQ894972 ABM85898 M28215 AAA60245 X13903 CAA32103 NM_001292048 NP_001278977 NM_004162 NP_004153
Function The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulation of filopodia extension. {ECO:0000269|PubMed:10818110, ECO:0000269|PubMed:14617813, ECO:0000269|PubMed:14978216, ECO:0000269|PubMed:15378032, ECO:0000269|PubMed:16410077}.
Subcellular Location Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Early endosome membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. Melanosome. Cytoplasmic vesicle {ECO:0000250}. Cell projection, ruffle {ECO:0000250}. Membrane. Cytoplasm, cytosol. Note=Enriched in stage I melanosomes. Alternates between membrane-bound and cytosolic forms.
Top Pathways Amyotrophic lateral sclerosis (ALS), Endocytosis, Vasopressin-regulated water reabsorption, Phagosome, Amoebiasis

Rab5 (C8B1) Rabbit mAb - 3547 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone C8B1
Western blot analysis of extracts from various cell lines using Rab5 (C8B1) Rabbit mAb.

Rab5 Antibody - 2143 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell extracts using Rab5 Antibody.

Rab 5 (D-11) - sc-46692 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Rab 5 (D-11): sc-46692. Western blot analysis of Rab 5 expression in non-transfected 293: sc-110760 (A), human Rab 5A transfected 293: sc-110852 (B) and HL-60 (C) whole cell lysates.

Rab 5 (FL-215) - sc-28570 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Rab 5 (FL-215): sc-28570. Western blot analysis of Rab 5 expression in non-transfected 293: sc-110760 (A), human Rab 5A transfected 293: sc-110852 (B) and HL-60 (C) whole cell lysates.

Rab 5A (A-12) - sc-166622 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Rab 5A (A-12): sc-166622. Western blot analysis of Rab 5A expression in HL-60 whole cell lysate.

Rab 5A (D-2) - sc-166601 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Rab 5A (D-2): sc-166601. Western blot analysis of Rab 5A expression in non-transfected: sc-110760 (A) and human Rab 5A transfected: sc-112278 (B) 293 whole cell lysates.

Rab 5A (E-11) - sc-166600 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Rab 5A (E-11): sc-166600. Western blot analysis of Rab 5A expression in non-transfected: sc-110760 (A) and human Rab 5A transfected: sc-112278 (B) 293 whole cell lysates.

Rab 5A (P-12) - sc-26566 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Rab 5A (P-12): sc-26566. Western blot analysis of Rab 5A expression in non-transfected 293T: sc-117752 (A), human Rab 5A transfected 293T: sc-173656 (B) and HL-60 (C) whole cell lysates.

Rab 5A (S-19) - sc-309 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Rab 5A (S-19): sc-309. Western blot analysis of human recombinant Rab 5A protein.

Rab 5A (3A4) - sc-130010 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Rab 5A (3A4): sc-130010. Western blot analysis of Rab 5A expression in non-transfected: sc-117752 (A) and mouse Rab 5A transfected: sc-122910 (B) 293T whole cell lysates.

Anti-Rab5 antibody - ab55657 from Abcam

Prices $376.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal

Anti-Rab5 antibody [3A4] - ab66746 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3A4
Anti-Rab5 antibody [3A4] (ab66746) at 1/500 dilution + extracts of mouse brain at 45 µgSecondaryHRP-conjugated goat anti-mousedeveloped using the ECL technique

Anti-Rab5 antibody [EPR5438] - Early Endosome Marker - ab109534 from Abcam

Prices $388.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5438
All lanes : purified at 1/5000 dilutionLane 1 : Mouse brainLane 2 : Rat brainLysates/proteins at 10 µg per lane.SecondaryHRP goat anti-rabbit (H+L) at 1/1000 dilution

Anti-Rab5 antibody - C-terminal - ab175877 from Abcam

Prices $384.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Rab5 antibody - C-terminal (ab175877) at 1/1000 dilution + HL60 cell lysate at 35 µg

Anti-Rab5 antibody - C-terminal - ab190215 from Abcam

Prices $384.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin fixed, paraffin embedded Human prostate tissue labeling Rab5 with ab190215 at 1/50 dilution.

Anti-RAB5 Antibody - LS-C104843 from LifeSpan Bioscience

Prices $340.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RAB5 Antibody - LS-C153117 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RAB5 Antibody (Atto 390) - LS-C232062 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RAB5 Antibody (Atto 488) - LS-C232064 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RAB5 Antibody (Atto 565) - LS-C232063 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RAB5 Antibody (Atto 594) - LS-C232065 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RAB5 Antibody (Atto 655) - LS-C232067 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RAB5 Antibody (Atto 633) - LS-C232066 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RAB5 Antibody (Atto 680) - LS-C232068 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RAB5 Antibody (AP) - LS-C232070 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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