CBX5

Gene Symbol	CBX5
Entrez Gene	23468
Alt Symbol	HEL25, HP1, HP1A
Species	Human
Gene Type	protein-coding
Description	chromobox homolog 5
Other Description	HP1 alpha homolog|HP1-ALPHA|HP1Hs alpha|antigen p25|chromobox homolog 5 (HP1 alpha homolog, Drosophila)|chromobox protein homolog 5|epididymis luminal protein 25|heterochromatin protein 1 homolog alpha|heterochromatin protein 1-alpha
Swissprots	B2R8T9 P45973
Accessions	EAW96758 EAW96759 EAW96760 P45973 AF147443 AK023520 AK055641 AK056315 AK095108 AK313506 BAG36286 BC006821 AAH06821 BC030149 BC047432 BP236173 BP336150 CR457418 CAG33699 DT217255 EU446624 ABZ92153 EU446784 ABZ92313 EU794599 ACJ13653 L07515 AAA72327 S62077 AAB26994 U26311 AAC50553 NM_001127321 NP_001120793 NM_001127322 NP_001120794 NM_012117 NP_036249
Function	Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. {ECO:0000269|PubMed:19783980}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:10460410}. Chromosome {ECO:0000269|PubMed:10460410}. Chromosome, centromere {ECO:0000269|PubMed:10460410}. Note=Component of centromeric and pericentromeric heterochromatin. Associates with chromosomes during mitosis. Associates specifically with chromatin during metaphase and anaphase.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-CBX5-cDNA-Clone - DC02024 from Abgent, a WuXi AppTec company Prices $257.85 Sizes 10 µg Species Human Accession BC006821

CBX5 - MBS1271476 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC006821

Human HP1 alpha/CBX5 Gene ORF cDNA clone in cloning vector - HG14669-G from Sino Biological Species Human

Human HP1 alpha/CBX5 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14669-CF from Sino Biological Species Human

Human HP1 alpha/CBX5 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG14669-ANR from Sino Biological Species Human

Human HP1 alpha/CBX5 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14669-NM from Sino Biological Species Human

Human HP1 alpha/CBX5 Gene ORF cDNA clone expression plasmid, C-His tag - HG14669-CH from Sino Biological Species Human

Human HP1 alpha/CBX5 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14669-CM from Sino Biological Species Human

Human HP1 alpha/CBX5 Gene ORF cDNA clone expression plasmid - HG14669-UT from Sino Biological Species Human

Human HP1 alpha/CBX5 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG14669-ANG from Sino Biological Species Human

Human HP1 alpha/CBX5 Gene ORF cDNA clone expression plasmid, C-HA tag - HG14669-CY from Sino Biological Species Human

Human HP1 alpha/CBX5 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14669-NF from Sino Biological Species Human

Human HP1 alpha/CBX5 Gene ORF cDNA clone expression plasmid, N-His tag - HG14669-NH from Sino Biological Species Human

Human HP1 alpha/CBX5 Gene ORF cDNA clone expression plasmid, N-HA tag - HG14669-NY from Sino Biological Species Human

Human HP1 alpha/CBX5 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG14669-ACG from Sino Biological Species Human

Human CBX5 ORF Clone(NM_001127321.1) - CDCR348602 from Creative biogene Species Human

Human CBX5 ORF Clone(NM_001127322.1) - CDCR348604 from Creative biogene Species Human

Human CBX5 ORF Clone (BC006821) - CDCS407786 from Creative biogene Species Human Accession P45973

Human CBX5 ORF clone (BC006821) - CDCB158839 from Creative biogene Species Human

Human CBX5 cDNA Clone(NM_001127321.1) - CDFH002810 from Creative biogene Species Human

Human CBX5 cDNA Clone(NM_001127322.1) - CDFH002811 from Creative biogene Species Human

Human Chromobox Homolog 5 Gene - orb142179 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

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