CBX5

Gene Symbol CBX5
Entrez Gene 23468
Alt Symbol HEL25, HP1, HP1A
Species Human
Gene Type protein-coding
Description chromobox homolog 5
Other Description HP1 alpha homolog|HP1-ALPHA|HP1Hs alpha|antigen p25|chromobox homolog 5 (HP1 alpha homolog, Drosophila)|chromobox protein homolog 5|epididymis luminal protein 25|heterochromatin protein 1 homolog alpha|heterochromatin protein 1-alpha
Swissprots B2R8T9 P45973
Accessions EAW96758 EAW96759 EAW96760 P45973 AF147443 AK023520 AK055641 AK056315 AK095108 AK313506 BAG36286 BC006821 AAH06821 BC030149 BC047432 BP236173 BP336150 CR457418 CAG33699 DT217255 EU446624 ABZ92153 EU446784 ABZ92313 EU794599 ACJ13653 L07515 AAA72327 S62077 AAB26994 U26311 AAC50553 NM_001127321 NP_001120793 NM_001127322 NP_001120794 NM_012117 NP_036249
Function Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. {ECO:0000269|PubMed:19783980}.
Subcellular Location Nucleus {ECO:0000269|PubMed:10460410}. Chromosome {ECO:0000269|PubMed:10460410}. Chromosome, centromere {ECO:0000269|PubMed:10460410}. Note=Component of centromeric and pericentromeric heterochromatin. Associates with chromosomes during mitosis. Associates specifically with chromatin during metaphase and anaphase.

HP1α CRISPR/Cas9 KO Plasmid (h) - sc-401403 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HP1α HDR Plasmid (h) - sc-401403-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HP1α Double Nickase Plasmid (h) - sc-401403-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HP1α Double Nickase Plasmid (h2) - sc-401403-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HP1α CRISPR Activation Plasmid (h) - sc-401403-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HP1α CRISPR Activation Plasmid (h2) - sc-401403-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HP1α Lentiviral Activation Particles (h) - sc-401403-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HP1α Lentiviral Activation Particles (h2) - sc-401403-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HP1α siRNA (h) - sc-37737 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HP1α shRNA Plasmid (h) - sc-37737-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HP1α shRNA (h) Lentiviral Particles - sc-37737-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HP1 alpha RNAi - H00023468-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU134611 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5429 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5429 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CBX5 siRNA (Human) - CRH8289 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CBX5 - MBS8224984 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CBX5 (NM_012117.2) - SHH255533 from Creative biogene

Category siRNA
Species Reactivities Human

Human CBX5 siRNA - orb268791 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CBX5 shRNA Plasmid (Human) - CHH8289 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
Search more