PDPN

Gene Symbol	PDPN
Entrez Gene	10630
Alt Symbol	AGGRUS, GP36, GP40, Gp38, HT1A-1, OTS8, PA2.26, T1A, T1A-2, T1A2, TI1A
Species	Human
Gene Type	protein-coding
Description	podoplanin
Other Description	PA2.26 antigen|T1-alpha|glycoprotein 36|glycoprotein, 36-KD|hT1alpha-1|hT1alpha-2|lung type I cell membrane associated glycoprotein|lung type-I cell membrane-associated glycoprotein (T1A-2)
Swissprots	Q8NBQ8 O95128 E9PB68 A9Z1Y2 F6QWX5 Q86YL7 Q7L375 Q8NBR3 O60836 B2R6J8
Accessions	EAW51691 EAW51692 EAW51693 EAW51694 Q86YL7 AB127958 BAD04046 AF030427 AAD01899 AF030428 AAD01900 AF390106 AAM73655 AJ225022 CAA12352 AK075327 BAC11550 AK075345 BAC11557 AK307705 AK307706 AK312607 BAG35495 AW022996 AY194238 AAO22143 BC014668 AAH14668 BC022812 AAH22812 BE887331 BF340649 BQ212176 BQ214601 CA312590 CD245679 XM_006710295 XP_006710358 NM_001006624 NP_001006625 NM_001006625 NP_001006626 NM_006474 NP_006465 NM_198389 NP_938203
Function	May be involved in cell migration and/or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. Required for normal lung cell proliferation and alveolus formation at birth. Induces platelet aggregation. Does not have any effect on folic acid or amino acid transport. Does not function as a water channel or as a regulator of aquaporin-type water channels. {ECO:0000250|UniProtKB:Q62011, ECO:0000269|PubMed:14522983, ECO:0000269|PubMed:15231832, ECO:0000269|PubMed:15515019, ECO:0000269|PubMed:9651190}.
Subcellular Location	Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell projection, filopodium membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell projection, lamellipodium membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell projection, microvillus membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell projection, ruffle membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Localized to actin-rich microvilli and plasma membrane projections such as filopodia, lamellipodia and ruffles. {ECO:0000250}.
Tissue Specificity	Highly expressed in placenta, lung, skeletal muscle and brain. Weakly expressed in brain, kidney and liver. In placenta, expressed on the apical plasma membrane of endothelium. In lung, expressed in alveolar epithelium. Up-regulated in colorectal tumors and expressed in 25% of early oral squamous cell carcinomas. {ECO:0000269|PubMed:10393083, ECO:0000269|PubMed:14522983, ECO:0000269|PubMed:15515019}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PDPN / Podoplanin ELISA Kit (Sandwich ELISA) - LS-F6466 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 0.156-10 ng/ml

Rat PDPN / Podoplanin ELISA Kit (Sandwich ELISA) - LS-F7062 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 0.156-10 ng/ml

Mouse PDPN / Podoplanin ELISA Kit (Sandwich ELISA) - LS-F9294 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.054 ng/ml Range 0.156-10 ng/ml

Human Podoplanin (PDPN) ELISA Kit - abx055403 from Abbexa Category ELISA Kit

Human Podoplanin ELISA Kit - abx152798 from Abbexa Category ELISA Kit Sensitivity 0.056 ng/ml Range 0.156 ng/ml - 10 ng/ml

Podoplanin, PDPN, Human, ELISA Kit - E-EL-H1810 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Podoplanin (PDPN), Human, ELISA Kit - CSB-EL017739HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Podoplanin, Human, ELISA Kit - E01P0082 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 0.5-10ng/ml

Podoplanin, PDPN, Human, ELISA Kit - E2095h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/mL

Podoplanin, PDPN, Rabbit, ELISA Kit - E-EL-RB2032 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Podoplanin, PDPN, Chicken, ELISA Kit - E-EL-Ch1996 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Podoplanin, PDPN, Porcine, ELISA Kit - E-EL-P1421 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Podoplanin, PDPN, Sheep, ELISA Kit - E-EL-S0931 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Podoplanin, PDPN, Monkey, ELISA Kit - E-EL-MK1389 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human PDPN ELISA Kit - HP0089 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine PDPN ELISA Kit - AP0089 from NeoScientific Category ELISA Kit Prices $300.00, $480.00 Sizes 100 µl, 200 µl

PDPN, ELISA Kit - MBS2512404 from MyBioSource Category ELISA Kit Prices $490.00, $585.00, $2,475.00, $4,360.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.469ng/mL Range 0.781-50ng/mL

PDPN, ELISA Kit - MBS2516017 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

PDPN, ELISA Kit - MBS2509134 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

PDPN, ELISA Kit - MBS2513516 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.938ng/mL Range 1.563-100ng/mL

PDPN, ELISA Kit - MBS2516358 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of Rat PDPN is 0.094ng/mL (The sensitivity of this assay, or lowest detectable limit (LDL) was defined as the lowest protein concentration that could be differentiated from zero). Range 0.156-10ng/mL

PDPN, ELISA Kit - MBS2512020 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

PDPN, ELISA Kit - MBS2504939 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of Human PDPN is 0.094ng/mL (The sensitivity of this assay, or lowest detectable limit (LDL) was defined as the lowest protein concentration that could be differentiated from zero). Range 0.156-10ng/mL

PDPN, ELISA Kit - MBS2503927 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.938ng/mL Range 1.563-100ng/mL

Human PDPN(Podoplanin) ELISA Kit - E-EL-H1810 from Elabscience Category ELISA Kit Sensitivity 0.10 ng/mL Range 0.16—10 ng/mL

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