PDPN

Gene Symbol	PDPN
Entrez Gene	10630
Alt Symbol	AGGRUS, GP36, GP40, Gp38, HT1A-1, OTS8, PA2.26, T1A, T1A-2, T1A2, TI1A
Species	Human
Gene Type	protein-coding
Description	podoplanin
Other Description	PA2.26 antigen\|T1-alpha\|glycoprotein 36\|glycoprotein, 36-KD\|hT1alpha-1\|hT1alpha-2\|lung type I cell membrane associated glycoprotein\|lung type-I cell membrane-associated glycoprotein (T1A-2)
Swissprots	Q8NBQ8 O95128 E9PB68 A9Z1Y2 F6QWX5 Q86YL7 Q7L375 Q8NBR3 O60836 B2R6J8
Accessions	EAW51691 EAW51692 EAW51693 EAW51694 Q86YL7 AB127958 BAD04046 AF030427 AAD01899 AF030428 AAD01900 AF390106 AAM73655 AJ225022 CAA12352 AK075327 BAC11550 AK075345 BAC11557 AK307705 AK307706 AK312607 BAG35495 AW022996 AY194238 AAO22143 BC014668 AAH14668 BC022812 AAH22812 BE887331 BF340649 BQ212176 BQ214601 CA312590 CD245679 XM_006710295 XP_006710358 NM_001006624 NP_001006625 NM_001006625 NP_001006626 NM_006474 NP_006465 NM_198389 NP_938203
Function	May be involved in cell migration and/or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. Required for normal lung cell proliferation and alveolus formation at birth. Induces platelet aggregation. Does not have any effect on folic acid or amino acid transport. Does not function as a water channel or as a regulator of aquaporin-type water channels. {ECO:0000250\|UniProtKB:Q62011, ECO:0000269\|PubMed:14522983, ECO:0000269\|PubMed:15231832, ECO:0000269\|PubMed:15515019, ECO:0000269\|PubMed:9651190}.
Subcellular Location	Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell projection, filopodium membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell projection, lamellipodium membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell projection, microvillus membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell projection, ruffle membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Localized to actin-rich microvilli and plasma membrane projections such as filopodia, lamellipodia and ruffles. {ECO:0000250}.
Tissue Specificity	Highly expressed in placenta, lung, skeletal muscle and brain. Weakly expressed in brain, kidney and liver. In placenta, expressed on the apical plasma membrane of endothelium. In lung, expressed in alveolar epithelium. Up-regulated in colorectal tumors and expressed in 25% of early oral squamous cell carcinomas. {ECO:0000269\|PubMed:10393083, ECO:0000269\|PubMed:14522983, ECO:0000269\|PubMed:15515019}.

Human AGGRUS Gene - orb91516 from Biorbyt

Prices	$255.00
Sizes	10 μg
Species	Human

PDPN - MBS1274595 from MyBioSource

Prices	$175.00
Sizes	10ug plasmid + 200ul glycerol stock
Species	Human
Accession	BC014668

Human Podoplanin Gene ORF cDNA clone in cloning vector - HG11065-M from Sino Biological

Species	Human

Human Podoplanin Gene ORF cDNA clone expression plasmid, C-His tag - HG11065-CH from Sino Biological

Species	Human

Human Podoplanin Gene ORF cDNA clone expression plasmid, N-Flag tag - HG11065-NF from Sino Biological

Species	Human

Human Podoplanin Gene ORF cDNA clone expression plasmid, N-Myc tag - HG11065-NM from Sino Biological

Species	Human

Human Podoplanin Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11065-CF from Sino Biological

Species	Human

Human Podoplanin Gene ORF cDNA clone expression plasmid, C-Myc tag - HG11065-CM from Sino Biological

Species	Human

Human Podoplanin Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG11065-ACG from Sino Biological

Species	Human

Human Podoplanin Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG11065-ACR from Sino Biological

Species	Human

Human Podoplanin Gene ORF cDNA clone expression plasmid, C-HA tag - HG11065-CY from Sino Biological

Species	Human

Human Podoplanin Gene ORF cDNA clone expression plasmid, N-HA tag - HG11065-NY from Sino Biological

Species	Human

Human Podoplanin Gene ORF cDNA clone expression plasmid - HG11065-UT from Sino Biological

Species	Human

Human Podoplanin Gene ORF cDNA clone expression plasmid, N-His tag - HG11065-NH from Sino Biological

Species	Human

Human PDPN ORF clone(NM_006474.4) - CDCL185687 from Creative biogene

Species	Human

Human PDPN ORF clone (NM_001006624.1) - CDCL147789 from Creative biogene

Species	Human

Mouse PDPN ORF clone (NM_001006625.1) - CDCL147791 from Creative biogene

Species	Human

Human PDPN ORF clone (NM_198389.2) - CDCL147794 from Creative biogene

Species	Human

Human PDPN ORF Clone (BC014668) - CDCS406281 from Creative biogene

Species	Human
Accession	E9PB68

Human PDPN cDNA Clone(NM_198389.2) - CDFG012581 from Creative biogene

Species	Human

Human PDPN cDNA Clone(NM_001006624.1) - CDFH014017 from Creative biogene

Species	Human

Human PDPN cDNA Clone(NM_001006625.1) - CDFH014018 from Creative biogene

Species	Human

Human PDPN cDNA Clone(NM_006474.4) - CDFH014019 from Creative biogene

Species	Human

Search more