STAM

Gene Symbol STAM
Entrez Gene 8027
Alt Symbol STAM-1, STAM1
Species Human
Gene Type protein-coding
Description signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
Other Description HSE1 homolog|signal transducing adapter molecule 1
Swissprots Q92783 Q8N6D9 D3DRU5 B0YJ99
Accessions ACA06077 ACA06078 CAY55994 EAW86207 EAW86208 EAW86209 Q92783 AK024383 AK303083 BAG64194 AK314405 BAG37028 AU118708 BC030586 AAH30586 BX647982 U43899 AAC50734 XM_005252603 XP_005252660 XM_011519695 XP_011517997 NM_003473 NP_003464 NR_037774
Function Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.
Subcellular Location Cytoplasm {ECO:0000305}. Early endosome membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Tissue Specificity Ubiquitously expressed. {ECO:0000269|PubMed:8780729}.
Top Pathways Jak-STAT signaling pathway, Endocytosis

STAM1 Antibody - 13053 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using STAM1 Antibody.

STAM (B-2) - sc-133093 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
STAM (B-2): sc-133093. Western blot analysis of STAM expression in K-562 (A) and HeLa (B) whole cell lysates.

STAM (15) - sc-293057 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
STAM (15): sc-293057. Western blot analysis of STAM expression in K-562 whole cell lysate.

STAM (C-20) - sc-6919 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
STAM (C-20): sc-6919. Western blot analysis of STAM expression in HeLa whole cell lysate.

STAM (D-3) - sc-133092 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
STAM (D-3): sc-133092. Western blot analysis of STAM expression in K-562 (A) and HeLa (B) whole cell lysates.

STAM (H-175) - sc-33588 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
STAM (H-175): sc-33588. Western blot analysis of STAM expression in HeLa (A), MCF7 (B) and Jurkat (C) whole cell lysates.

STAM (N-17) - sc-6920 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
STAM (N-17): sc-6920. Western blot analysis of STAM expression in K-562 (A) and Jurkat (B) whole cell lysates.

Anti-STAM1 antibody - ab56346 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human small intestine tissue, staining STAM1 with ab56346 at 3 &microg/ml.

Anti-STAM1 antibody - ab155527 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-STAM1 antibody (ab155527) at 1/1000 dilutionLane 1 : Jurkat whole cell lysateLane 2 : Raji whole cell lysateLane 3 : K562 whole cell lysateLane 4 : NCI-H929 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-STAM1 antibody - ab168676 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-STAM1 antibody (ab168676) at 1 µg/mlLane 1 : STAM transfected 293T lysateLane 2 : Non-transfected 293T lysateLysates/proteins at 15 µl per lane.

Anti-STAM1 antibody - C-terminal - ab135766 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-STAM1 antibody - C-terminal (ab135766) at 1/100 dilution + HeLa cell line lysate at 35 µgdeveloped using the ECL technique

Anti-STAM1 / STAM Antibody (Internal) - LS-C94907 from LifeSpan Bioscience

Prices $325.00
Sizes 500 µg
Host Sheep
Clonality Polyclonal

Anti-STAM1 / STAM Antibody (Internal) - LS-C94878 from LifeSpan Bioscience

Prices $325.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal

Anti-STAM1 / STAM Antibody (aa149-165) - LS-C91679 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-STAM1 / STAM Antibody (C-Terminus, AP) - LS-C220787 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STAM1 / STAM Antibody (C-Terminus, APC) - LS-C220788 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STAM1 / STAM Antibody (C-Terminus, Biotin) - LS-C220789 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STAM1 / STAM Antibody (C-Terminus, FITC) - LS-C220790 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STAM1 / STAM Antibody (C-Terminus, Azide-free, HRP) - LS-C220791 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STAM1 / STAM Antibody (aa149-165, clone 29C678) - LS-C495 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 29C678
Western blot of STAM on 15 ug/lane HeLa cell lysate using antibody.

Anti-STAM1 / STAM Antibody (C-Terminus, PE) - LS-C220792 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STAM1 / STAM Antibody (aa400-450) - LS-C289979 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-STAM1 / STAM Antibody (aa300-350) - LS-C289978 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-STAM1 / STAM Antibody (C-Terminus) - LS-C328760 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STAM1 / STAM Antibody (aa151-200) - LS-C146066 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
STAM antibody LS-C146066 Western blot of HeLa Cell lysate. Antibody concentration 1 ug/ml.
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