STAM

Gene Symbol STAM
Entrez Gene 8027
Alt Symbol STAM-1, STAM1
Species Human
Gene Type protein-coding
Description signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
Other Description HSE1 homolog|signal transducing adapter molecule 1
Swissprots Q92783 Q8N6D9 D3DRU5 B0YJ99
Accessions ACA06077 ACA06078 CAY55994 EAW86207 EAW86208 EAW86209 Q92783 AK024383 AK303083 BAG64194 AK314405 BAG37028 AU118708 BC030586 AAH30586 BX647982 U43899 AAC50734 XM_005252603 XP_005252660 XM_011519695 XP_011517997 NM_003473 NP_003464 NR_037774
Function Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.
Subcellular Location Cytoplasm {ECO:0000305}. Early endosome membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Tissue Specificity Ubiquitously expressed. {ECO:0000269|PubMed:8780729}.
Top Pathways Jak-STAT signaling pathway, Endocytosis

STAM CRISPR/Cas9 KO Plasmid (h) - sc-402697 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

STAM HDR Plasmid (h) - sc-402697-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STAM Double Nickase Plasmid (h) - sc-402697-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STAM Double Nickase Plasmid (h2) - sc-402697-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STAM CRISPR Activation Plasmid (h) - sc-402697-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

STAM CRISPR Activation Plasmid (h2) - sc-402697-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

STAM Lentiviral Activation Particles (h) - sc-402697-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STAM Lentiviral Activation Particles (h2) - sc-402697-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STAM siRNA (h) - sc-41043 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

STAM shRNA Plasmid (h) - sc-41043-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

STAM shRNA (h) Lentiviral Particles - sc-41043-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

STAM-1 RNAi - H00008027-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU032411 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20692 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20692 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

STAM siRNA (Human) - CRH5343 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

STAM - MBS8212033 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human STAM (NM_003473.3) - SHH419184 from Creative biogene

Category siRNA
Species Reactivities Human

Human STAM siRNA - orb265845 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

STAM shRNA Plasmid (Human) - CHH5343 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

STAM miRNA 3'UTR clone - MiUTR3H-04488 from Creative biogene

Species Reactivities Human
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