NEXN

Gene Symbol	NEXN
Entrez Gene	91624
Alt Symbol	CMH20, NELIN
Species	Human
Gene Type	protein-coding
Description	nexilin (F actin binding protein)
Other Description	nexilin
Swissprots	Q9Y2V1 B4DPZ7 Q14CC3 Q16081 A0PJ84 Q0D2H2 Q96DL0 Q14CC2 Q7Z2X0 Q0ZGT2
Accessions	EAX06359 EAX06360 EAX06361 EAX06362 Q0ZGT2 AA249326 AF114264 AAD29607 AF176780 AAQ13658 AK057954 BAB71622 AK127535 AK293201 BAG56741 AK298565 BAG60759 AK300728 BAG62401 AK307487 AY211912 AAO65165 BC017827 AAH17827 BC055084 AAH55084 BC111395 AAI11396 BC114444 AAI14445 BC114445 AAI14446 BQ009808 BX648546 CR936630 CAI56773 DC412178 DQ464902 ABE97925 S67069 AAB28815 XM_005271322 XP_005271379 XM_005271323 XP_005271380 XM_005271324 XP_005271381 XM_005271325 XP_005271382 XM_005271326 XP_005271383 XM_005271327 XP_005271384 NM_001172309 NP_001165780 NM_144573 NP_653174
Function	Involved in regulating cell migration through association with the actin cytoskeleton. Has an essential role in the maintenance of Z line and sarcomere integrity. {ECO:0000269|PubMed:12053183, ECO:0000269|PubMed:15823560, ECO:0000269|PubMed:19881492}.
Subcellular Location	Cytoplasm, cytoskeleton {ECO:0000250}. Cell junction, adherens junction {ECO:0000250|UniProtKB:Q9Z2J4}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250}. Note=Localizes to the cell-matrix AJ. Not found at the cell-cell AJ (By similarity). {ECO:0000250|UniProtKB:Q9Z2J4, ECO:0000269|PubMed:15823560}.
Tissue Specificity	Abundantly expressed in heart and skeletal muscle, and at lower levels in placenta, lung, liver and pancreas. Also expressed in HeLaS3 and MOLT-4 cell lines. {ECO:0000269|PubMed:12053183, ECO:0000269|PubMed:15823560, ECO:0000269|PubMed:19881492}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

NEXN / Nexilin Antibody Blocking Peptide - LS-E17380 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Nexilin Blocking Peptide - 33R-2372 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Recombinant Nexilin (NEXN) - RPH548Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Nexilin (NEXN) - RPH548Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Nexilin (NEXN) - RPH548Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Recombinant Nexilin (NEXN) - RPH548Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Nexilin(NEXN) - CSB-YP605897HU CSB-EP605897HU CSB-BP605897HU CSB-MP605897HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Nexilin Recombinant Protein Antigen - NBP1-92179PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

NEXN Peptide, Human - M34GP10321H from Creative Peptides Category Peptide Source Synthetic. Species Human

NEXN fusion protein - Ag26938 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

Nexilin, Recombinant Protein - MBS2029227 from MyBioSource Category Protein Prices $190.00, $395.00, $610.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Mouse

Nexilin (NEXN), Recombinant Protein - MBS1429897 from MyBioSource Category Protein Prices $1,475.00, $1,475.00, $1,705.00, $1,705.00, $2,520.00, $2,520.00, $2,960.00, $2,960.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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