NEXN

Gene Symbol NEXN
Entrez Gene 91624
Alt Symbol CMH20, NELIN
Species Human
Gene Type protein-coding
Description nexilin (F actin binding protein)
Other Description nexilin
Swissprots Q9Y2V1 B4DPZ7 Q14CC3 Q16081 A0PJ84 Q0D2H2 Q96DL0 Q14CC2 Q7Z2X0 Q0ZGT2
Accessions EAX06359 EAX06360 EAX06361 EAX06362 Q0ZGT2 AA249326 AF114264 AAD29607 AF176780 AAQ13658 AK057954 BAB71622 AK127535 AK293201 BAG56741 AK298565 BAG60759 AK300728 BAG62401 AK307487 AY211912 AAO65165 BC017827 AAH17827 BC055084 AAH55084 BC111395 AAI11396 BC114444 AAI14445 BC114445 AAI14446 BQ009808 BX648546 CR936630 CAI56773 DC412178 DQ464902 ABE97925 S67069 AAB28815 XM_005271322 XP_005271379 XM_005271323 XP_005271380 XM_005271324 XP_005271381 XM_005271325 XP_005271382 XM_005271326 XP_005271383 XM_005271327 XP_005271384 NM_001172309 NP_001165780 NM_144573 NP_653174
Function Involved in regulating cell migration through association with the actin cytoskeleton. Has an essential role in the maintenance of Z line and sarcomere integrity. {ECO:0000269|PubMed:12053183, ECO:0000269|PubMed:15823560, ECO:0000269|PubMed:19881492}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000250}. Cell junction, adherens junction {ECO:0000250|UniProtKB:Q9Z2J4}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250}. Note=Localizes to the cell-matrix AJ. Not found at the cell-cell AJ (By similarity). {ECO:0000250|UniProtKB:Q9Z2J4, ECO:0000269|PubMed:15823560}.
Tissue Specificity Abundantly expressed in heart and skeletal muscle, and at lower levels in placenta, lung, liver and pancreas. Also expressed in HeLaS3 and MOLT-4 cell lines. {ECO:0000269|PubMed:12053183, ECO:0000269|PubMed:15823560, ECO:0000269|PubMed:19881492}.

NELIN CRISPR/Cas9 KO Plasmid (h) - sc-413904 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELIN HDR Plasmid (h) - sc-413904-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELIN Double Nickase Plasmid (h) - sc-413904-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELIN Double Nickase Plasmid (h2) - sc-413904-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELIN CRISPR Activation Plasmid (h) - sc-413904-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELIN CRISPR Activation Plasmid (h2) - sc-413904-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELIN Lentiviral Activation Particles (h) - sc-413904-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELIN Lentiviral Activation Particles (h2) - sc-413904-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELIN siRNA (h) - sc-88506 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NELIN shRNA Plasmid (h) - sc-88506-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NELIN shRNA (h) Lentiviral Particles - sc-88506-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN15231 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15231 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07858 from Sigma-Aldrich

Category miRNA

NEXN siRNA (Human) - CRJ4058 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Nexn (NM_144573.3) - SHH351636 from Creative biogene

Category siRNA
Species Reactivities Human

Human NEXN siRNA - orb274559 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NEXN shRNA Plasmid (Human) - CHJ4058 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NEXN miRNA 3'UTR clone - MiUTR1H-06730 from Creative biogene

Species Reactivities Human
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