| Gene Symbol |
PTGR2
|
| Entrez Gene |
145482
|
| Alt Symbol |
HEL-S-298, PGR2, ZADH1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
prostaglandin reductase 2
|
| Other Description |
15-oxoprostaglandin 13-reductase|15-oxoprostaglandin-delta13-reductase|PRG-2|epididymis secretory protein Li 298|zinc binding alcohol dehydrogenase, domain containing 1|zinc-binding alcohol dehydrogenase domain-containing protein 1
|
| Swissprots |
Q3L8A4 Q6MZH8 Q8N8N7
|
| Accessions |
EAW81132 EAW81133 EAW81134 EAW81135 Q8N8N7 AK096410 BAC04781 AK309188 AK311280 AY346133 AAR05101 AY424308 AAR82927 BC059364 AAH59364 BP357520 BU616297 BX641118 CAE46055 DR158023 FJ224334 ACI46026 HQ448502 ADQ32982 NM_001146154 NP_001139626 NM_001146155 NP_001139627 NM_152444 NP_689657
|
| Function |
Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto- PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}.
|
| Tissue Specificity |
Widely expressed. {ECO:0000269|PubMed:15004468}.
|
![Western Blot: ZADH1 Overexpression Lysate (Adult Normal) [NBL1-14942] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ZADH1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/3542_ZADH1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-14942-img0002.jpg)