Gene Symbol | PTGR2 |
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Entrez Gene | 145482 |
Alt Symbol | HEL-S-298, PGR2, ZADH1 |
Species | Human |
Gene Type | protein-coding |
Description | prostaglandin reductase 2 |
Other Description | 15-oxoprostaglandin 13-reductase|15-oxoprostaglandin-delta13-reductase|PRG-2|epididymis secretory protein Li 298|zinc binding alcohol dehydrogenase, domain containing 1|zinc-binding alcohol dehydrogenase domain-containing protein 1 |
Swissprots | Q3L8A4 Q6MZH8 Q8N8N7 |
Accessions | EAW81132 EAW81133 EAW81134 EAW81135 Q8N8N7 AK096410 BAC04781 AK309188 AK311280 AY346133 AAR05101 AY424308 AAR82927 BC059364 AAH59364 BP357520 BU616297 BX641118 CAE46055 DR158023 FJ224334 ACI46026 HQ448502 ADQ32982 NM_001146154 NP_001139626 NM_001146155 NP_001139627 NM_152444 NP_689657 |
Function | Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto- PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:15004468}. |
Human ZADH1 full length protein - ab124605 from Abcam
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PTGR2 / PGR2 Antibody Blocking Peptide - LS-E2009 from LifeSpan Bioscience
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PTGR2 / PGR2 Antibody Blocking Peptide - LS-E19100 from LifeSpan Bioscience
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ZADH1 Recombinant Protein - H00145482-P01 from Novus Biologicals
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ZADH1 Partial Recombinant Protein - H00145482-Q01 from Novus Biologicals
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Recombinant Human ZADH1 Protein - NBP1-99021 from Novus Biologicals
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PTGR2-Antibody-N-term-Blocking-peptide - BP12869a from Abgent, a WuXi AppTec company
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Human PTGR2 protein - orb169113 from Biorbyt
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PTGR2 peptide - orb218735 from Biorbyt
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PTGR2 protein (His tag) - 80R-2246 from Fitzgerald
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ZADH1 Blocking Peptide - 33R-4040 from Fitzgerald
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PTGR2 Blocking Peptide - abx064066 from Abbexa
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ZADH1 (1-351, His-tag) - AR50329PU-N from Acris Antibodies
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ZADH1 (1-351, His-tag) - AR50329PU-S from Acris Antibodies
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ZADH1 - H00145482-P01-10 from Acris Antibodies
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ZADH1 - H00145482-P01-25 from Acris Antibodies
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ZADH1 - H00145482-Q01-10 from Acris Antibodies
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ZADH1 - H00145482-Q01-25 from Acris Antibodies
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PTGR2, 1-351aa, Human, His tag, E.coli - 01-P1505 from ARP American Research Products
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PTGR2 fusion protein - Ag5352 from Proteintech Group
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PTGR2 Human - ENPS-608 from NeoScientific
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Recombinant Human Prostaglandin Reductase 2 Enzyme - BP002773-ENZ-601 from Syd Labs
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Recombinant Human Prostaglandin Reductase 2, His-tagged - PTGR2-1957H from Creative Biomart
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Recombinant Human PTGR2, His-tagged - PTGR2-15845H from Creative Biomart
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Recombinant Human PTGR2, GST-tagged - PTGR2-2049H from Creative Biomart
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