USP19

Gene Symbol USP19
Entrez Gene 10869
Alt Symbol ZMYND9
Species Human
Gene Type protein-coding
Description ubiquitin specific peptidase 19
Other Description deubiquitinating enzyme 19|ubiquitin carboxyl-terminal hydrolase 19|ubiquitin specific protease 19|ubiquitin thioesterase 19|ubiquitin thiolesterase 19|ubiquitin-specific-processing protease 19|zinc finger MYND domain-containing protein 9
Swissprots A6H8U2 Q86XV9 Q641Q9 B4DTZ0 A5PKX8 Q6NZY8 E7EN22 B4DGT3 O94966 E9PEG8 Q3KQW4 E7ETS0
Accessions EAW64955 EAW64956 EAW64957 O94966 AB020698 BAA74914 AK294756 BAG57894 AK296447 BAG59098 AK300425 BAG62152 BC014934 BC048269 AAH48269 BC065909 AAH65909 BC082241 AAH82241 BC106029 AAI06030 BC128088 BC142660 AAI42661 BC142727 AAI42728 BC146752 AAI46753 DC323791 DC332671 EF036501 ABO65087 XM_005264823 XP_005264880 XM_005264824 XP_005264881 XM_005264825 XP_005264882 XM_005264826 XP_005264883 XM_005264827 XP_005264884 XM_005264829 XP_005264886 XM_005264830 XP_005264887 XM_005264831 XP_005264888 XM_006712946 XP_006713009 XM_006712947 XP_006713010 XM_006712948 XP_006713011 XM_006712949 XP_006713012 XM_006712950 XP_006713013 XM_006712951 XP_006713014 XM_006712952 XP_006713015 XM_006712953 XP_006713016 NM_001199160 NP_001186089 NM_001199161 NP_001186090 NM_001199162 NP_001186091 NM_006677 NP_006668
Function Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin- dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic- reticulum-associated degradation (ERAD) substrates. Regulates the stability of BIRC2/c-IAP1 and BIRC3/c-IAP2 by preventing their ubiquitination. Required for cells to mount an appropriate response to hypoxia and rescues HIF1A from degradation in a non- catalytic manner. Plays an important role in 17 beta-estradiol (E2)-inhibited myogenesis. Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis. Exhibits a preference towards 'Lys-63'-linked Ubiquitin chains. {ECO:0000269|PubMed:19465887, ECO:0000269|PubMed:21849505, ECO
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:19465887}; Single-pass membrane protein {ECO:0000269|PubMed:19465887}.

USP19 (S-16) - sc-99713 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

USP19 (V-14) - sc-99715 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-USP19 antibody - ab93159 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-USP19 antibody - ab167059 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-USP19 antibody (ab167059) at 1/500 dilutionLane 1 : NIH3T3 cell extractLane 2 : NIH3T3 cell extract with immunizing peptide

Anti-USP19 antibody - ab68527 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-USP19 antibody (ab68527) at 1/500 dilutionLane 1 : transfected 293T cell lysateLane 2 : non transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-USP19 antibody [EPR14816] - ab189518 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14816
Flow cytometric analysis of Jurkat cells (left histogram) labeling USP19 with ab189518 at 1/250 dilution compared to negative control cells (right histogram). Secondary antibody FITC-conjugated goat-anti-rabbit IgG used at 1/150 diution.

Anti-USP19 antibody - C-terminal - ab174235 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-USP19 antibody - C-terminal (ab174235) at 1/50 dilution + Jurkat cell lysate at 35 µg

Anti-USP19 antibody - N-terminal - ab195646 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-USP19 antibody - N-terminal (ab195646) at 1/100 dilution + mouse testis lysate at 50 µg

Anti-USP19 Antibody (aa350-362) - LS-C87304 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-USP19 Antibody (C-Terminus, AP) - LS-C226637 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP19 Antibody (C-Terminus, Biotin) - LS-C226639 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP19 Antibody (C-Terminus, APC) - LS-C226638 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP19 Antibody (C-Terminus, Azide-free, HRP) - LS-C226641 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP19 Antibody (C-Terminus, FITC) - LS-C226640 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP19 Antibody (aa900-950) - LS-C288378 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-USP19 Antibody (C-Terminus, PE) - LS-C226642 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP19 Antibody (aa439-484) - LS-C313991 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-USP19 Antibody (aa1-50) - LS-C288379 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-USP19 Antibody (C-Terminus, Azide-free) - LS-C329060 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP19 Antibody (aa1289-1319) - LS-C99561 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of hUSP19-L1304 in Jurkat cell line lysates (35 ug/lane). USP19 (arrow) was detected using the purified antibody.

Anti-USP19 Antibody - LS-C343778 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of full length USP19 and its degradation fragments in mouse testis lysate (50ug) by Western blot using USP19polyclonal antibody.

Anti-USP19 Antibody (aa391-440) IHC-plus™ - LS-B8595 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-KIAA0891 / USP19 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8595 dilution 5 ug/ml.

USP19 Antibody - NBP1-68695 from Novus Biologicals

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: USP19 Antibody [NBP1-68695] - Analysis of extracts from NIH-3T3 cells, using . The lane on the right is treated with the synthesized peptide.

USP19 Antibody - NB100-79829 from Novus Biologicals

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: USP19 Antibody [NB100-79829] - Detection of Human USP19/ZMYND9 on HeLa whole cell lysate using NB10-79827. USP19/ZMYND9 was also immunoprecipitated by rabbit anti-USP19/ZMYND9 antibody NB100-79828.

USP19 Antibody - NB100-79828 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: USP19 Antibody [NB100-79828] - Detection of Human USP19/ZMYND9 on HeLa whole cell lysate using NB100-79828. USP19/ZMYND9 was also immunoprecipitated by rabbit anti-USP19/ZMYND9 antibody NB100-79829.
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