Gene Symbol | SNCG |
---|---|
Entrez Gene | 6623 |
Alt Symbol | BCSG1, SR |
Species | Human |
Gene Type | protein-coding |
Description | synuclein, gamma (breast cancer-specific protein 1) |
Other Description | breast cancer-specific gene 1 protein|gamma-synuclein|persyn|synoretin |
Swissprots | O15104 Q96P61 O76070 |
Accessions | AAC27738 AAC36586 EAW80315 EAW80316 EAW80317 EAW80318 O76070 AF010126 AAB64109 AF017256 AAC36550 AF411524 AAL05870 AK223367 BAD97087 AK312141 BAG35077 BC014098 AAH14098 BP346786 CR541788 CAG46587 CR541790 CAG46589 DQ892334 ABM83260 DQ892505 ABM83431 DQ895719 ABM86645 EU019993 ABS18760 EU176715 ABW03516 XM_011540105 XP_011538407 NM_003087 NP_003078 |
Function | Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, perinuclear region {ECO:0000269|PubMed:11746666}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:11746666}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:11746666}. Note=Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle. |
Tissue Specificity | Highly expressed in brain, particularly in the substantia nigra. Also expressed in the corpus callosum, heart, skeletal muscle, ovary, testis, colon and spleen. Weak expression in pancreas, kidney and lung. |
Human gamma Synuclein full length protein - ab48712 from Abcam
|
||||||||||
Human gamma Synuclein full length protein - ab169723 from Abcam
|
||||||||||
Human gamma Synuclein full length protein - ab172814 from Abcam
|
||||||||||
Human gamma Synuclein peptide - ab46713 from Abcam
|
||||||||||
Synuclein-gamma Recombinant Protein - H00006623-P01 from Novus Biologicals
|
||||||||||
Synuclein-gamma Partial Recombinant Protein - H00006623-Q01 from Novus Biologicals
|
||||||||||
Recombinant Human gamma-Synuclein Protein - NBC1-18329 from Novus Biologicals
|
||||||||||
SYUG-Antibody-C-term-Blocking-peptide - BP11775b from Abgent, a WuXi AppTec company
|
||||||||||
SNCG Protein (OPPA01307) - OPPA01307 from Aviva Systems Biology
|
||||||||||
Human SNCG protein - orb163504 from Biorbyt
|
||||||||||
Human Gammalpha Synuclein protein - orb81148 from Biorbyt
|
||||||||||
Human SNCG protein - orb244552 from Biorbyt
|
||||||||||
gamma Synuclein protein - 30R-1062 from Fitzgerald
|
||||||||||
Gamma-synuclein Blocking Peptide - abx063284 from Abbexa
|
||||||||||
Gamma-Synuclein / SNCG (1-127) - SA6012 from Acris Antibodies
|
||||||||||
Gamma-Synuclein / SNCG (1-127) - SA6012X from Acris Antibodies
|
||||||||||
Gamma-Synuclein / SNCG - H00006623-P01-10 from Acris Antibodies
|
||||||||||
Gamma-Synuclein / SNCG - H00006623-P01-25 from Acris Antibodies
|
||||||||||
Gamma-Synuclein / SNCG - H00006623-Q01-10 from Acris Antibodies
|
||||||||||
Gamma-Synuclein / SNCG - H00006623-Q01-25 from Acris Antibodies
|
||||||||||
Gamma-Synuclein, Human Recombinant - 228-10592-1 from RayBiotech
|
||||||||||
Recombinant Human Synuclein, gamma - 228-10592-2 from RayBiotech
|
||||||||||
Recombinant Human Synuclein, gamma - 228-10592-3 from RayBiotech
|
||||||||||
gamma-Synuclein, Human, Recombinant, E.coli - 01-2214 from ARP American Research Products
|
||||||||||
SNCG, Human, Recombinant - 19-CF67 from ARP American Research Products
|