SNCG

Gene Symbol SNCG
Entrez Gene 6623
Alt Symbol BCSG1, SR
Species Human
Gene Type protein-coding
Description synuclein, gamma (breast cancer-specific protein 1)
Other Description breast cancer-specific gene 1 protein|gamma-synuclein|persyn|synoretin
Swissprots O15104 Q96P61 O76070
Accessions AAC27738 AAC36586 EAW80315 EAW80316 EAW80317 EAW80318 O76070 AF010126 AAB64109 AF017256 AAC36550 AF411524 AAL05870 AK223367 BAD97087 AK312141 BAG35077 BC014098 AAH14098 BP346786 CR541788 CAG46587 CR541790 CAG46589 DQ892334 ABM83260 DQ892505 ABM83431 DQ895719 ABM86645 EU019993 ABS18760 EU176715 ABW03516 XM_011540105 XP_011538407 NM_003087 NP_003078
Function Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm, perinuclear region {ECO:0000269|PubMed:11746666}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:11746666}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:11746666}. Note=Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle.
Tissue Specificity Highly expressed in brain, particularly in the substantia nigra. Also expressed in the corpus callosum, heart, skeletal muscle, ovary, testis, colon and spleen. Weak expression in pancreas, kidney and lung.

γ-synuclein (C-20) - sc-10699 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

γ-synuclein (E-20) - sc-10698 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
γ-synuclein (E-20): sc-10698. Western blot analysis of human recombinant synuclein, γ (BCSGI).

γ-synuclein (B-21) - sc-135676 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
γ-synuclein (B-21): sc-135676. Western blot analysis of γ-synuclein expression in HT29 whole cell lysate.

γ-synuclein (8H11) - sc-135575 from Santa Cruz Biotechnology

Prices $295.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
γ-synuclein (8H11): sc-135575. Western blot analysis of γ-synuclein expression in human γ-synuclein transfected (A) and non-transfected (B) 293T whole cell lysates.

Anti-gamma Synuclein antibody - ab55424 from Abcam

Prices $400.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab55424 staining gamma Synclein in Rat retina cells by ICC/IF (Immunocytochemistry/immunofluorescence). Cells were fixed with formaldehyde, permeabilized by freezing and blocked with 2% serum for 1 hour at 24°C. Samples were incubated with primary antibody (1/100 in 2% Triton + 2% Serum in PBS) for 8 hours at 4°C. An Alexa Fluor® 594-conjugated Donkey anti-rabbit IgG polyclonal (1/500) was used as the secondary antibody.See Abreview

Anti-gamma Synuclein antibody - ab6169 from Abcam

Prices $390.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab6169 was tested on recombinant protein only, 100ng recombinant protein each lane. 1= alpha-synuclein, 2 =  beta-synuclein, 3 = gamma-synuclein. The primary was 1/2000, secondary was alkaline phosphatase conjugated anti-rabbit from Sigma. We did not try it on crude samples such as brain or other tissue homogenates.

Anti-gamma Synuclein antibody - ab49206 from Abcam

Prices $373.00
Sizes 500 µl
Host Sheep
Clonality Polyclonal

Anti-gamma Synuclein antibody - ab133704 from Abcam

Prices $384.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human adrenal cortex tissue labelling gamman Synuclein with ab133704 at 5 µg/ml, followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-gamma Synuclein antibody - ab89462 from Abcam

Host Mouse
Clonality Monoclonal
Anti-gamma Synuclein antibody (ab89462) at 1/500 dilution + tagged, recombinant human gamma Synuclein protein fragment (the immunogen) at 0.2 µg

Anti-gamma Synuclein antibody - ab46201 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-gamma Synuclein antibody (ab46201) at 0.5 µg/ml + Human gamma Synuclein full length protein (ab48712) at 0.05 µgSecondaryGoat polyclonal to rabbit IgG - H&L - Pre adsorbed (HRP) at 1/3000 dilutionPerformed under reducing conditions.Observed band size : 15 kDa (why is the actual band size different from the predicted?)

Anti-gamma Synuclein antibody [1H10D2] - ab47966 from Abcam

Prices $385.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1H10D2
Anti-gamma Synuclein antibody [1H10D2] (ab47966) at 1/500 dilution + Truncated gamma Synuclein recombinant protein

Anti-gamma Synuclein antibody [EP1539Y] - ab52633 from Abcam

Prices $381.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1539Y
Anti-gamma Synuclein antibody [EP1539Y] (ab52633) at 1/2000 dilution + fetal brain lysate

Anti-SNCG / Gamma-Synuclein Antibody (aa1-115) - LS-C296562 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant SNCG / Gamma-Synuclein.

Anti-SNCG / Gamma-Synuclein Antibody (clone 1H10D2) - LS-C47178 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1H10D2

Anti-SNCG / Gamma-Synuclein Antibody (aa1-123) - LS-C314659 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant SNCG / Gamma-Synuclein.

Anti-SNCG / Gamma-Synuclein Antibody (clone EP1539Y) - LS-C49932 from LifeSpan Bioscience

Prices $480.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1539Y
IHC of paraffin-embedded human brain using anti-gamma Synuclein antibody.

Anti-SNCG / Gamma-Synuclein Antibody (clone 2C3) - LS-C198234 from LifeSpan Bioscience

Prices $355.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2C3
Western Blot analysis of SNCG expression in transfected 293T cell line by SNCG monoclonal antibody (M01), clone 2C3.Lane 1: SNCG transfected lysate(13.3 KDa).Lane 2: Non-transfected lysate.

Anti-SNCG / Gamma-Synuclein Antibody (Ala111) - LS-C176305 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of Synuclein (A111) pAb in paraffin-embedded human lung carcinoma tissue.

Anti-SNCG / Gamma-Synuclein Antibody (aa78-127) IHC-plus™ - LS-B7047 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SNCG antibody IHC of human brain, cortex neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7047 concentration 5 ug/ml.

Anti-SNCG / Gamma-Synuclein Antibody - LS-C335252 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human thyroid cancer using SNCG antibody at dilution of 1:200 (x400 lens).

Anti-SNCG / Gamma-Synuclein Antibody IHC-plus™ - LS-B7908 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-Gamma-Synuclein / SNCG antibody IHC of human vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7908 dilution 1:200.

Anti-SNCG / Gamma-Synuclein Antibody (aa114-127) - LS-C17983 from LifeSpan Bioscience

Prices $495.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-SNCG / Gamma-Synuclein Antibody (C-Terminus) - LS-C17987 from LifeSpan Bioscience

Prices $590.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SNCG / Gamma-Synuclein Antibody (C-Terminus) - LS-C17991 from LifeSpan Bioscience

Prices $415.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-SNCG / Gamma-Synuclein Antibody - LS-C39458 from LifeSpan Bioscience

Prices $355.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
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