| Gene Symbol | FRAT1 |
|---|---|
| Entrez Gene | 10023 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | frequently rearranged in advanced T-cell lymphomas 1 |
| Other Description | FRAT-1|proto-oncogene FRAT1 |
| Swissprots | Q5JTI1 Q8NE74 Q8TDW9 Q92837 |
| Accessions | EAW49950 EAW49951 Q92837 AB074890 BAB86352 AK307245 BC034476 AAH34476 BE041458 U58975 AAB97096 NM_005479 NP_005470 NM_181355 |
| Function | Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis. {ECO:0000269|PubMed:12556519}. |
| Subcellular Location | Cytoplasm. |
| Top Pathways | Wnt signaling pathway |
frequently rearranged in advanced T-cell lymphomas, ELISA Kit - MBS9328905 from MyBioSource
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Human FRAT1 ELISA Kit - E015559 from Biobool
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