| Gene Symbol |
FRAT1
|
| Entrez Gene |
10023
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
frequently rearranged in advanced T-cell lymphomas 1
|
| Other Description |
FRAT-1|proto-oncogene FRAT1
|
| Swissprots |
Q5JTI1 Q8NE74 Q8TDW9 Q92837
|
| Accessions |
EAW49950 EAW49951 Q92837 AB074890 BAB86352 AK307245 BC034476 AAH34476 BE041458 U58975 AAB97096 NM_005479 NP_005470 NM_181355
|
| Function |
Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis. {ECO:0000269|PubMed:12556519}.
|
| Subcellular Location |
Cytoplasm.
|
| Top Pathways |
Wnt signaling pathway
|