Gene Symbol | F7 |
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Entrez Gene | 2155 |
Alt Symbol | SPCA |
Species | Human |
Gene Type | protein-coding |
Description | coagulation factor VII (serum prothrombin conversion accelerator) |
Other Description | FVII coagulation protein|coagulation factor VII|eptacog alfa|proconvertin |
Swissprots | Q5JVF1 Q9UD53 Q9UD52 Q9UD54 Q5JVF2 B0YJC8 P08709 Q14339 |
Accessions | AAA51983 AAC50211 AAL66184 AAP33841 ABD17891 ABO20833 ABO20834 ACA06107 ACA06108 CAL24227 CCQ42967 EAX09182 EAX09183 P08709 AI076552 AK298404 BAG60634 AK310779 AK311565 AK311682 AY423856 AAQ94106 BC130468 AAI30469 CB156039 DB184045 EF421855 ABN79862 EU557239 ACB87203 HQ258414 ADR83168 M13232 AAA88040 XM_006719963 XP_006720026 XM_011537474 XP_011535776 XM_011537475 XP_011535777 XM_011537476 XP_011535778 XM_011537477 XP_011535779 NM_000131 NP_000122 NM_001267554 NP_001254483 NM_019616 NP_062562 NR_051961 |
Function | Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium. |
Subcellular Location | Secreted. |
Tissue Specificity | Plasma. |
Top Pathways | Complement and coagulation cascades |
Factor VII Human ELISA Kit - ab108829 from Abcam
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Factor VII Human ELISA Kit (with plasma controls) - ab168545 from Abcam
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Factor VII Human SimpleStep ELISA™ Kit - ab190810 from Abcam
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Factor VIIa Human Chromogenic Activity Assay Kit - ab137995 from Abcam
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Human F7 / Factor VII ELISA Kit (Sandwich ELISA) - LS-F5043 from LifeSpan Bioscience
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Mouse F7 / Factor VII ELISA Kit (Sandwich ELISA) - LS-F7471 from LifeSpan Bioscience
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Rat F7 / Factor VII ELISA Kit (Sandwich ELISA) - LS-F7481 from LifeSpan Bioscience
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Human F7 / Factor VII ELISA Kit (Sandwich ELISA) - LS-F10416 from LifeSpan Bioscience
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Mouse F7 / Factor VII ELISA Kit (Sandwich ELISA) - LS-F11409 from LifeSpan Bioscience
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Rat F7 / Factor VII ELISA Kit (Sandwich ELISA) - LS-F11408 from LifeSpan Bioscience
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Rabbit F7 / Factor VII ELISA Kit - LS-F11407 from LifeSpan Bioscience
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Coagulation Factor VII Colorimetric Assay Kit - KA0971 from Novus Biologicals
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Human Coagulation Factor VII ELISA Kit - abx053115 from Abbexa
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Human F7 ELISA Kit - abx151469 from Abbexa
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Coagulation factor VII, FVII, Human, ELISA Kit - CSB-E12909h from ARP American Research Products
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Coagulation Factor VII (F7), Human, ELISA Kit - SEB874Hu from ARP American Research Products
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Coagulation factor VII, F7, Human, ELISA Kit - E1874h from ARP American Research Products
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Coagulation Factor VII, Human, ELISA Kit - E01F0014 from ARP American Research Products
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Coagulation Factor VII, F7, Human, ELISA Kit - E-EL-H0758 from ARP American Research Products
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Coagulation Factor VII, F VII, Rat, ELISA Kit - E-EL-R2376 from ARP American Research Products
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Coagulation Factor VII, F7, Rabbit, ELISA Kit - E-EL-RB1581 from ARP American Research Products
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Coagulation Factor VII, F7, Chicken, ELISA Kit - E-EL-Ch0904 from ARP American Research Products
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Coagulation Factor VII, F7, Porcine, ELISA Kit - E-EL-P0484 from ARP American Research Products
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Coagulation Factor VII, F7, Sheep, ELISA Kit - E-EL-S0300 from ARP American Research Products
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Coagulation Factor VII, F7, Monkey, ELISA Kit - E-EL-MK1522 from ARP American Research Products
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