F7

Gene Symbol F7
Entrez Gene 2155
Alt Symbol SPCA
Species Human
Gene Type protein-coding
Description coagulation factor VII (serum prothrombin conversion accelerator)
Other Description FVII coagulation protein|coagulation factor VII|eptacog alfa|proconvertin
Swissprots Q5JVF1 Q9UD53 Q9UD52 Q9UD54 Q5JVF2 B0YJC8 P08709 Q14339
Accessions AAA51983 AAC50211 AAL66184 AAP33841 ABD17891 ABO20833 ABO20834 ACA06107 ACA06108 CAL24227 CCQ42967 EAX09182 EAX09183 P08709 AI076552 AK298404 BAG60634 AK310779 AK311565 AK311682 AY423856 AAQ94106 BC130468 AAI30469 CB156039 DB184045 EF421855 ABN79862 EU557239 ACB87203 HQ258414 ADR83168 M13232 AAA88040 XM_006719963 XP_006720026 XM_011537474 XP_011535776 XM_011537475 XP_011535777 XM_011537476 XP_011535778 XM_011537477 XP_011535779 NM_000131 NP_000122 NM_001267554 NP_001254483 NM_019616 NP_062562 NR_051961
Function Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.
Subcellular Location Secreted.
Tissue Specificity Plasma.
Top Pathways Complement and coagulation cascades

Factor VII CRISPR/Cas9 KO Plasmid (h) - sc-402582 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor VII HDR Plasmid (h) - sc-402582-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor VII Double Nickase Plasmid (h) - sc-402582-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor VII Double Nickase Plasmid (h2) - sc-402582-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor VII CRISPR Activation Plasmid (h) - sc-402582-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor VII CRISPR Activation Plasmid (h2) - sc-402582-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor VII Lentiviral Activation Particles (h) - sc-402582-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor VII Lentiviral Activation Particles (h2) - sc-402582-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor VII siRNA (h) - sc-40401 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Factor VII shRNA Plasmid (h) - sc-40401-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Factor VII shRNA (h) Lentiviral Particles - sc-40401-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Coagulation Factor VII RNAi - H00002155-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU079311 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1633 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1633 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

F7 siRNA (Human) - CRH1498 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Coagulation Factor VII RNAi - H00002155-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

F7 - MBS828905 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

F7 shRNA Plasmid (Human) - CHH1498 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

F7 miRNA 3'UTR clone - MiUTR3H-13057 from Creative biogene

Species Reactivities Human

F7 miRNA 3'UTR clone - MiUTR3H-13058 from Creative biogene

Species Reactivities Human
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