F7

Gene Symbol F7
Entrez Gene 2155
Alt Symbol SPCA
Species Human
Gene Type protein-coding
Description coagulation factor VII (serum prothrombin conversion accelerator)
Other Description FVII coagulation protein|coagulation factor VII|eptacog alfa|proconvertin
Swissprots Q5JVF1 Q9UD53 Q9UD52 Q9UD54 Q5JVF2 B0YJC8 P08709 Q14339
Accessions AAA51983 AAC50211 AAL66184 AAP33841 ABD17891 ABO20833 ABO20834 ACA06107 ACA06108 CAL24227 CCQ42967 EAX09182 EAX09183 P08709 AI076552 AK298404 BAG60634 AK310779 AK311565 AK311682 AY423856 AAQ94106 BC130468 AAI30469 CB156039 DB184045 EF421855 ABN79862 EU557239 ACB87203 HQ258414 ADR83168 M13232 AAA88040 XM_006719963 XP_006720026 XM_011537474 XP_011535776 XM_011537475 XP_011535777 XM_011537476 XP_011535778 XM_011537477 XP_011535779 NM_000131 NP_000122 NM_001267554 NP_001254483 NM_019616 NP_062562 NR_051961
Function Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.
Subcellular Location Secreted.
Tissue Specificity Plasma.
Top Pathways Complement and coagulation cascades

Factor VII (CaFVII-22) - sc-101369 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Factor VII (CaFVII-22): sc-101369. Immunoperoxidase staining of formalin fixed, paraffin-embedded human ovary tissue showing staining of plasma in blood vessels.

Factor VII (H-64) - sc-366000 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Factor VII (H-64): sc-366000. Western blot analysis of Factor VII expression in NCI-H1299 whole cell lysate (A) and human heart tissue extract (B).

Factor VII (K-20) - sc-16343 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Factor VII Antibody (K-20): sc-16343. Immunoperoxidase staining of formalin fixed, paraffin-embedded human gall bladder tissue showing cytoplasmic and membrane staining of glandular cells.

Factor VII (RFF-VII/2) - sc-59507 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

Factor VII (MA-HFVII) - sc-81679 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Factor VII (C-18) - sc-16344 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Factor VII (M-19) - sc-16347 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Factor VII (M-19): sc-16347. Immunoperoxidase staining of formalin fixed, paraffin-embedded human gall bladder tissue showing cytoplasmic and membrane staining of glandular cells.

Factor VII (RFF-VII/1) - sc-59506 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

Factor VII (AHVII-5031) - sc-73460 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-Factor VII + VIIa antibody - C-terminal - ab191845 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Factor VII antibody - ab97614 from Abcam

Prices $385.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab97614 stained HepG2 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab97614, 5µg/ml) overnight at +4°C. The secondary antibody (green) was ab96899, DyLight® 488 goat anti-rabbit IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM

Anti-Factor VII antibody - ab104564 from Abcam

Prices $378.00
Sizes 250 µg
Host Sheep
Clonality Polyclonal
ab104564, at 5 ug/ml, staining Factor VII in formalin-fixed, paraffin-embedded Human Liver by Immunohistochemistry, using a biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-Factor VII antibody - ab61359 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-Factor VII antibody - ab30906 from Abcam

Prices $370.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-Factor VII antibody - ab61369 from Abcam

Prices $370.00
Sizes 1 mg
Host Sheep
Clonality Polyclonal

Anti-Factor VII antibody - ab171819 from Abcam

Host Mouse
Clonality Polyclonal
All lanes : Anti-Factor VII antibody (ab171819) at 1/500 dilutionLane 1 : Factor VII-transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilutiondeveloped using the ECL technique

Anti-Factor VII antibody - ab61963 from Abcam

Prices $370.00
Sizes 100 µl
Host Chicken
Clonality Polyclonal

Anti-Factor VII antibody [EP6185(2)] - ab151543 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP6185(2)
All lanes : Anti-Factor VII antibody [EP6185(2)] (ab151543) at 1/1000 dilutionLane 1 : Human placenta lysateLane 2 : Human serum lysateLane 3 : Human fetal liver lysateLane 4 : HepG2 cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-Factor VII antibody - C-terminal - ab197656 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Factor VII antibody - C-terminal (ab197656) at 1/400 dilutionLane 1 : mouse NIH 3T3 cell lysateLane 2 : 293T cell lysateLane 3 : Jurkat cell lysateLysates/proteins at 40 µg per lane.

Anti-Factor VIIa antibody - ab7053 from Abcam

Prices $369.00
Sizes 125 µg
Host Rabbit
Clonality Polyclonal

Anti-Factor VIIa antibody - ab61412 from Abcam

Prices $370.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal

Anti-F7 / Factor VII Antibody - LS-C23362 from LifeSpan Bioscience

Prices $265.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-F7 / Factor VII Antibody - LS-C23361 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-F7 / Factor VII Antibody (HRP) - LS-C23366 from LifeSpan Bioscience

Prices $455.00
Sizes 200 µg
Host Sheep
Clonality Polyclonal

Anti-F7 / Factor VII Antibody - LS-C36301 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
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