Gene Symbol | RGS3 |
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Entrez Gene | 5998 |
Alt Symbol | C2PA, RGP3 |
Species | Human |
Gene Type | protein-coding |
Description | regulator of G-protein signaling 3 |
Other Description | regulator of G-protein signalling 3 |
Swissprots | Q8NC47 Q8TD68 Q8TD59 Q5VXC1 Q5VXB8 Q8IUQ1 Q8NFN4 B3KUB2 Q8NFN5 Q6ZRM5 Q8NFN6 Q8WXA0 P49796 Q8WV02 A8K0V1 Q5VZ06 Q5VZ05 A6NHA0 |
Accessions | EAW87387 EAW87388 EAW87389 EAW87390 EAW87391 EAW87392 EAW87393 EAW87394 EAW87395 EAW87396 EAW87397 EAW87398 P49796 AF006609 AAB62725 AF131806 AF463495 AAL68829 AF490838 AAM33253 AF490839 AAM33254 AF490840 AAM33255 AF493927 AAM12641 AF493941 AAM12655 AK000377 BAA91125 AK054584 BAB70766 AK074977 BAC11328 AK096840 BAG53374 AK123387 BAG53899 AK125059 BAG54130 AK125094 BAC86049 AK128127 BAC87285 AK222888 BAD96608 AK226153 AK289666 BAF82355 AK301515 BAG63021 AK309971 AK310705 AY585192 AAT79495 BC018072 AAH18072 BC019039 AAH19039 BC042555 AAH42555 BE256545 BE298009 BM690084 BP257809 DA396065 DA680346 DA875652 DB031297 FJ423754 U27655 AAC50394 XM_006717219 XP_006717282 XM_006717220 XP_006717283 XM_006717222 XP_006717285 XM_006717224 XP_006717287 XM_006717225 XP_006717288 XM_006717226 XP_006717289 XM_006717230 XP_006717293 XM_011518893 XP_011517195 XM_011518894 XP_011517196 XM_011518895 XP_011517197 XM_011518896 XP_011517198 XM_011518897 XP_011517199 XM_011518898 XP_011517200 XM_011518899 XP_011517201 XM_011518900 XP_011517202 XM_011518901 XP_011517203 XR_929831 NM_001276260 NP_001263189 NM_001276261 NP_001263190 NM_001276262 NP_001263191 NM_001282922 NP_001269851 NM_001282923 NP_001269852 NM_017790 NP_060260 NM_130795 NP_570613 NM_134427 NP_602299 NM_144488 NP_652759 NM_144489 NP_652760 |
Function | Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G- protein-mediated release of inositol phosphates and activation of MAP kinases. {ECO:0000269|PubMed:10749886, ECO:0000269|PubMed:11294858, ECO:0000269|PubMed:8602223, ECO:0000269|PubMed:9858594}. |
Subcellular Location | Cytoplasm. Nucleus. Cell membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. Note=Long isoforms are cytoplasmic and associated with the plasma membrane. Short isoforms are nuclear. |
Top Pathways | Axon guidance |
RGS3 - MBS1268763 from MyBioSource
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RGS3 - MBS1268824 from MyBioSource
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RGS3 - MBS1268443 from MyBioSource
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Human RGS3 cDNA clone(NM_017790.3) - CDFG001033 from Creative Biomart
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Human RGS3 cDNA clone(NM_021106.3) - CDFG003209 from Creative Biomart
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Human RGS3 cDNA clone(NM_130795.2) - CDFG007604 from Creative Biomart
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Human RGS3 cDNA clone(NM_134427.1) - CDFG007826 from Creative Biomart
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Human RGS3 cDNA clone(NM_144488.4) - CDFG008493 from Creative Biomart
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Human RGS3 cDNA clone(NM_144489.2) - CDFG008494 from Creative Biomart
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Human RGS3 ORF Clone(NM_017790.3) - CDCR302403 from Creative Biomart
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Human RGS3 ORF Clone(NM_017790.3) - CDCR302404 from Creative Biomart
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Human RGS3 ORF Clone(NM_021106.3) - CDCR306611 from Creative Biomart
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Human RGS3 ORF Clone(NM_021106.3) - CDCR306612 from Creative Biomart
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Human RGS3 ORF Clone(NM_130795.2) - CDCR315562 from Creative Biomart
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Human RGS3 ORF Clone(NM_130795.2) - CDCR315563 from Creative Biomart
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Human RGS3 ORF Clone(NM_130795.2) - CDCR315564 from Creative Biomart
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Human RGS3 ORF Clone(NM_134427.1) - CDCR316248 from Creative Biomart
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Human RGS3 ORF Clone(NM_134427.1) - CDCR316249 from Creative Biomart
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Human RGS3 ORF Clone(NM_144488.4) - CDCR317453 from Creative Biomart
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Human RGS3 ORF Clone(NM_144488.4) - CDCR317454 from Creative Biomart
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Human RGS3 ORF Clone(NM_144489.2) - CDCR317455 from Creative Biomart
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Human RGS3 ORF Clone(NM_144489.2) - CDCR317456 from Creative Biomart
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Human RGS3 ORF Clone(NM_144489.2) - CDCR317457 from Creative Biomart
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Human RGS3 ORF Clone(NM_017790.3) - CDCR302403 from Creative biogene
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Human RGS3 ORF Clone(NM_021106.3) - CDCR306611 from Creative biogene
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