RGS3

Gene Symbol RGS3
Entrez Gene 5998
Alt Symbol C2PA, RGP3
Species Human
Gene Type protein-coding
Description regulator of G-protein signaling 3
Other Description regulator of G-protein signalling 3
Swissprots Q8NC47 Q8TD68 Q8TD59 Q5VXC1 Q5VXB8 Q8IUQ1 Q8NFN4 B3KUB2 Q8NFN5 Q6ZRM5 Q8NFN6 Q8WXA0 P49796 Q8WV02 A8K0V1 Q5VZ06 Q5VZ05 A6NHA0
Accessions EAW87387 EAW87388 EAW87389 EAW87390 EAW87391 EAW87392 EAW87393 EAW87394 EAW87395 EAW87396 EAW87397 EAW87398 P49796 AF006609 AAB62725 AF131806 AF463495 AAL68829 AF490838 AAM33253 AF490839 AAM33254 AF490840 AAM33255 AF493927 AAM12641 AF493941 AAM12655 AK000377 BAA91125 AK054584 BAB70766 AK074977 BAC11328 AK096840 BAG53374 AK123387 BAG53899 AK125059 BAG54130 AK125094 BAC86049 AK128127 BAC87285 AK222888 BAD96608 AK226153 AK289666 BAF82355 AK301515 BAG63021 AK309971 AK310705 AY585192 AAT79495 BC018072 AAH18072 BC019039 AAH19039 BC042555 AAH42555 BE256545 BE298009 BM690084 BP257809 DA396065 DA680346 DA875652 DB031297 FJ423754 U27655 AAC50394 XM_006717219 XP_006717282 XM_006717220 XP_006717283 XM_006717222 XP_006717285 XM_006717224 XP_006717287 XM_006717225 XP_006717288 XM_006717226 XP_006717289 XM_006717230 XP_006717293 XM_011518893 XP_011517195 XM_011518894 XP_011517196 XM_011518895 XP_011517197 XM_011518896 XP_011517198 XM_011518897 XP_011517199 XM_011518898 XP_011517200 XM_011518899 XP_011517201 XM_011518900 XP_011517202 XM_011518901 XP_011517203 XR_929831 NM_001276260 NP_001263189 NM_001276261 NP_001263190 NM_001276262 NP_001263191 NM_001282922 NP_001269851 NM_001282923 NP_001269852 NM_017790 NP_060260 NM_130795 NP_570613 NM_134427 NP_602299 NM_144488 NP_652759 NM_144489 NP_652760
Function Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G- protein-mediated release of inositol phosphates and activation of MAP kinases. {ECO:0000269|PubMed:10749886, ECO:0000269|PubMed:11294858, ECO:0000269|PubMed:8602223, ECO:0000269|PubMed:9858594}.
Subcellular Location Cytoplasm. Nucleus. Cell membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. Note=Long isoforms are cytoplasmic and associated with the plasma membrane. Short isoforms are nuclear.
Top Pathways Axon guidance

RGS3 CRISPR/Cas9 KO Plasmid (h) - sc-405065 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RGS3 HDR Plasmid (h) - sc-405065-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RGS3 Double Nickase Plasmid (h) - sc-405065-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RGS3 Double Nickase Plasmid (h2) - sc-405065-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RGS3 CRISPR Activation Plasmid (h) - sc-405065-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RGS3 CRISPR Activation Plasmid (h2) - sc-405065-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RGS3 Lentiviral Activation Particles (h) - sc-405065-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RGS3 Lentiviral Activation Particles (h2) - sc-405065-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RGS3 siRNA (h) - sc-40661 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RGS3 shRNA Plasmid (h) - sc-40661-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RGS3 shRNA (h) Lentiviral Particles - sc-40661-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RGS3 RNAi - H00005998-R06 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

RGS3 RNAi - H00005998-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

RGS3 RNAi - H00005998-R04 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

RGS3 RNAi - H00005998-R05 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

RGS3 RNAi - H00005998-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

RGS3 RNAi - H00005998-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN18228 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18228 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07223 from Sigma-Aldrich

Category miRNA

RGS3 siRNA (Human) - CRH4066 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RGS3 - MBS8211196 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RGS3 CRISPR/Cas9 KO Plasmid (h2) - sc-405065-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RGS3 HDR Plasmid (h2) - sc-405065-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human RGS3 (NM_144488.4) - SHH394964 from Creative biogene

Category siRNA
Species Reactivities Human
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