RGS3

Gene Symbol	RGS3
Entrez Gene	5998
Alt Symbol	C2PA, RGP3
Species	Human
Gene Type	protein-coding
Description	regulator of G-protein signaling 3
Other Description	regulator of G-protein signalling 3
Swissprots	Q8NC47 Q8TD68 Q8TD59 Q5VXC1 Q5VXB8 Q8IUQ1 Q8NFN4 B3KUB2 Q8NFN5 Q6ZRM5 Q8NFN6 Q8WXA0 P49796 Q8WV02 A8K0V1 Q5VZ06 Q5VZ05 A6NHA0
Accessions	EAW87387 EAW87388 EAW87389 EAW87390 EAW87391 EAW87392 EAW87393 EAW87394 EAW87395 EAW87396 EAW87397 EAW87398 P49796 AF006609 AAB62725 AF131806 AF463495 AAL68829 AF490838 AAM33253 AF490839 AAM33254 AF490840 AAM33255 AF493927 AAM12641 AF493941 AAM12655 AK000377 BAA91125 AK054584 BAB70766 AK074977 BAC11328 AK096840 BAG53374 AK123387 BAG53899 AK125059 BAG54130 AK125094 BAC86049 AK128127 BAC87285 AK222888 BAD96608 AK226153 AK289666 BAF82355 AK301515 BAG63021 AK309971 AK310705 AY585192 AAT79495 BC018072 AAH18072 BC019039 AAH19039 BC042555 AAH42555 BE256545 BE298009 BM690084 BP257809 DA396065 DA680346 DA875652 DB031297 FJ423754 U27655 AAC50394 XM_006717219 XP_006717282 XM_006717220 XP_006717283 XM_006717222 XP_006717285 XM_006717224 XP_006717287 XM_006717225 XP_006717288 XM_006717226 XP_006717289 XM_006717230 XP_006717293 XM_011518893 XP_011517195 XM_011518894 XP_011517196 XM_011518895 XP_011517197 XM_011518896 XP_011517198 XM_011518897 XP_011517199 XM_011518898 XP_011517200 XM_011518899 XP_011517201 XM_011518900 XP_011517202 XM_011518901 XP_011517203 XR_929831 NM_001276260 NP_001263189 NM_001276261 NP_001263190 NM_001276262 NP_001263191 NM_001282922 NP_001269851 NM_001282923 NP_001269852 NM_017790 NP_060260 NM_130795 NP_570613 NM_134427 NP_602299 NM_144488 NP_652759 NM_144489 NP_652760
Function	Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G- protein-mediated release of inositol phosphates and activation of MAP kinases. {ECO:0000269|PubMed:10749886, ECO:0000269|PubMed:11294858, ECO:0000269|PubMed:8602223, ECO:0000269|PubMed:9858594}.
Subcellular Location	Cytoplasm. Nucleus. Cell membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. Note=Long isoforms are cytoplasmic and associated with the plasma membrane. Short isoforms are nuclear.
Top Pathways	Axon guidance

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RGS3 full length protein - ab116894 from Abcam Category Protein Source Wheat germ Species Human

RGS3 Antibody Blocking Peptide - LS-E10526 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human RGS3 Protein - H00005998-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

RGS3 Blocking Peptide - 33R-4300 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

RGS3 - H00005998-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

RGS3 - H00005998-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

RGS3 fusion protein - Ag3177 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human RGS3 - RGS3-29967TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human RGS3, GST-tagged - RGS3-2280H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Regulator of G-protein signaling 3(RGS3) ,partial - CSB-YP019655HU CSB-EP019655HU CSB-BP019655HU CSB-MP019655HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

RGS3 Protein - abx164234 from Abbexa Category Protein Species Human, Mouse, Rat

RGS3 (transcript variant 4) - TP306471 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

RGS3 (transcript variant 1) - TP324058 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

RGS3 (full length, N-term HIS tag, transcript variant 5) - TP760493 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

RGS3-Blocking-Peptide-N-Term - BP21810a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

RGS3 Peptide, Human - M34GP13245H from Creative Peptides Category Peptide Source Synthetic. Species Human

RGS3 Recombinant Protein Antigen - NBP2-58942PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Regulator of G-protein signaling 3 (RGS3), partial, Recombinant Protein - MBS954293 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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