RGS3

Gene Symbol RGS3
Entrez Gene 5998
Alt Symbol C2PA, RGP3
Species Human
Gene Type protein-coding
Description regulator of G-protein signaling 3
Other Description regulator of G-protein signalling 3
Swissprots Q8NC47 Q8TD68 Q8TD59 Q5VXC1 Q5VXB8 Q8IUQ1 Q8NFN4 B3KUB2 Q8NFN5 Q6ZRM5 Q8NFN6 Q8WXA0 P49796 Q8WV02 A8K0V1 Q5VZ06 Q5VZ05 A6NHA0
Accessions EAW87387 EAW87388 EAW87389 EAW87390 EAW87391 EAW87392 EAW87393 EAW87394 EAW87395 EAW87396 EAW87397 EAW87398 P49796 AF006609 AAB62725 AF131806 AF463495 AAL68829 AF490838 AAM33253 AF490839 AAM33254 AF490840 AAM33255 AF493927 AAM12641 AF493941 AAM12655 AK000377 BAA91125 AK054584 BAB70766 AK074977 BAC11328 AK096840 BAG53374 AK123387 BAG53899 AK125059 BAG54130 AK125094 BAC86049 AK128127 BAC87285 AK222888 BAD96608 AK226153 AK289666 BAF82355 AK301515 BAG63021 AK309971 AK310705 AY585192 AAT79495 BC018072 AAH18072 BC019039 AAH19039 BC042555 AAH42555 BE256545 BE298009 BM690084 BP257809 DA396065 DA680346 DA875652 DB031297 FJ423754 U27655 AAC50394 XM_006717219 XP_006717282 XM_006717220 XP_006717283 XM_006717222 XP_006717285 XM_006717224 XP_006717287 XM_006717225 XP_006717288 XM_006717226 XP_006717289 XM_006717230 XP_006717293 XM_011518893 XP_011517195 XM_011518894 XP_011517196 XM_011518895 XP_011517197 XM_011518896 XP_011517198 XM_011518897 XP_011517199 XM_011518898 XP_011517200 XM_011518899 XP_011517201 XM_011518900 XP_011517202 XM_011518901 XP_011517203 XR_929831 NM_001276260 NP_001263189 NM_001276261 NP_001263190 NM_001276262 NP_001263191 NM_001282922 NP_001269851 NM_001282923 NP_001269852 NM_017790 NP_060260 NM_130795 NP_570613 NM_134427 NP_602299 NM_144488 NP_652759 NM_144489 NP_652760
Function Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G- protein-mediated release of inositol phosphates and activation of MAP kinases. {ECO:0000269|PubMed:10749886, ECO:0000269|PubMed:11294858, ECO:0000269|PubMed:8602223, ECO:0000269|PubMed:9858594}.
Subcellular Location Cytoplasm. Nucleus. Cell membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. Note=Long isoforms are cytoplasmic and associated with the plasma membrane. Short isoforms are nuclear.
Top Pathways Axon guidance

RGS3 (C-20) - sc-9304 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
RGS3 (C-20): sc-9304. Western blot analysis of RGS3 expression in Hep G2 whole cell lysate.

RGS3 (H-300) - sc-20759 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
RGS3 (H-300): sc-20759. Western blot analysis of RGS3 expression in non-transfected: sc-117752 (A) and mouse RGS3 transfected: sc-125903 (B) 293T whole cell lysates.

RGS3 (N-19) - sc-9303 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
RGS3 (N-19): sc-9303. Western blot analysis of RGS3 expression in non-transfected: sc-117752 (A) and mouse RGS3 transfected: sc-125903 (B) 293T whole cell lysates.

RGS3 (CC-Q7) - sc-100762 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
RGS3 (CC-Q7): sc-100762. Western blot analysis of RGS3 expression in non-transfected: sc-117752 (A) and human RGS3 transfected: sc-115637 (B) 293T whole cell lysates.

Anti-RGS3 antibody - ab57923 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
RGS3 antibody (ab57923) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human small Intestine.

Anti-RGS3 antibody - ab2564 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-RGS3 antibody (ab2564)Lane 2 : Anti-RGS3 antibody (ab2564) at 1 µg/mlLane 1 : mockLane 2 : transfected HEK293 cells (right lane)

Anti-RGS3 antibody - ab172308 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-RGS3 antibody (ab172308) at 1 µg/mlLane 1 : Lysate from 293T cells transfected with RGS3Lane 2 : Lysate from untransfected 293T cellsLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-RGS3 antibody [1E8-C7] - ab117729 from Abcam

Prices $464.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1E8-C7
All lanes : Anti-RGS3 antibody [1E8-C7] (ab117729) at 1/500 dilutionLane 1 : RGS3 transfected 293T cell lysateLane 2 : non-transfected 293T cell lysate

Anti-RGS3 antibody - C-terminal - ab191047 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded rat intestine tissue labeling RGS3 with ab191047 at 1 µg/ml.

Anti-RGS3 antibody - C-terminal - ab172283 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-RGS3 antibody - C-terminal (ab172283) at 1 µg/mlLane 1 : RGS3 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.

Anti-RGS3 Antibody (aa909-925) - LS-C313176 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
RGS3 antibody. IHC(P): Rat Intestine Tissue.

Anti-RGS3 Antibody (aa401-519) - LS-C9985 from LifeSpan Bioscience

Prices $575.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RGS3 Antibody (aa401-519) - LS-C9986 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RGS3 Antibody (C-Terminus) - LS-C31680 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RGS3 Antibody (aa111-129) - LS-C148040 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-RGS3 Antibody (aa1-193, Azide-free) - LS-C328517 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-RGS3 Antibody (aa401-519) - LS-C48288 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of RGS3 antibody LS-C48288.

Anti-RGS3 Antibody (C-Terminus) - LS-C82032 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HepG2 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-RGS3 Antibody (clone 1E8-C7) IHC-plus™ - LS-B5527 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1E8-C7
Anti-RGS3 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5527 concentration 5 ug/ml.

RGS3 Antibody - NBP1-58312 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RGS3 Antibody [NBP1-58312] - Human Heart lysate, concentration 0.2-1 ug/ml.

RGS3 Antibody (1E8-C7) - H00005998-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1E8-C7
Western Blot: RGS3 Antibody (1E8-C7) [H00005998-M01] - Analysis of RGS3 expression in transfected 293T cell line by RGS3 monoclonal antibody (M01), clone 1E8-C7.Lane 1: RGS3 transfected lysate(19.5 KDa).Lane 2: Non-transfected lysate.

RGS3 Antibody - NB120-2564 from Novus Biologicals

Prices $265.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: RGS3 Antibody [NB120-2564] - Western blot analysis of RGS3 in transfected HEK293 cells (right lane). The left lane is mock control.

RGS3 Antibody - H00005998-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: RGS3 Antibody [H00005998-D01P] - analysis of RGS3 expression in transfected 293T cell line by RGS3 MaxPab rabbit polyclonal antibody. Lane 1: RGS3 transfected lysate (19.50 KDa). Lane 2: Non-transfected lysate.

RGS3 Antibody - H00005998-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: RGS3 Antibody [H00005998-B01P] - Analysis of RGS3 expression in transfected 293T cell line by RGS3 polyclonal antibody. Lane 1: RGS3 transfected lysate(18.48 KDa). Lane 2: Non-transfected lysate.

Anti-RGS3 antibody produced in mouse - SAB1406389 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-RGS3: <B>Cat. No. SAB1406389</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~18.5 kDa using RGS3 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.
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