MESP2

Gene Symbol	MESP2
Entrez Gene	145873
Alt Symbol	SCDO2, bHLHc6
Species	Human
Gene Type	protein-coding
Description	mesoderm posterior basic helix-loop-helix transcription factor 2
Other Description	class C basic helix-loop-helix protein 6|mesoderm posterior 2 homolog|mesoderm posterior protein 2
Swissprots	Q0VG99 Q7RTU2
Accessions	DAA00304 Q0VG99 AL360139 BC111413 AAI11414 NM_001039958 NP_001035047
Function	Transcription factor with important role in somitogenesis. Defines the rostrocaudal patterning of the somite by participating in distinct Notch pathways. Regulates also the FGF signaling pathway. Specifies the rostral half of the somites. Generates rostro-caudal polarity of somites by down-regulating in the presumptive rostral domain DLL1, a Notch ligand. Participates in the segment border formation by activating in the anterior presomitic mesoderm LFNG, a negative regulator of DLL1-Notch signaling. Acts as a strong suppressor of Notch activity. Together with MESP1 is involved in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm.
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MESP2 Antibody Blocking Peptide - LS-E13240 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MESP2 Blocking Peptide - 33R-8337 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MESP2 Blocking Peptide - abx161160 from Abbexa Category Peptide Species Human, Mouse, Rat

MESP2 fusion protein - ag18082 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

MESP2 fusion protein - ag16345 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

MESP2 Blocking Peptide - CBP3659 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

Recombinant Human Mesoderm posterior protein 2(MESP2) - CSB-YP613150HU CSB-EP613150HU CSB-BP613150HU CSB-MP613150HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

MESP2-Antibody-N-term-Blocking-peptide - BP5705a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MESP2 Peptide, Human - M34GP09413H from Creative Peptides Category Peptide Source Synthetic. Species Human

Mesoderm posterior protein 2 (MESP2), Recombinant Protein - MBS1392443 from MyBioSource Category Protein Prices $1,170.00, $1,170.00, $1,400.00, $1,400.00, $1,875.00, $1,875.00, $2,340.00, $2,340.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

MESP2 peptide - orb234534 from Biorbyt Category Peptide

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