MESP2

Gene Symbol MESP2
Entrez Gene 145873
Alt Symbol SCDO2, bHLHc6
Species Human
Gene Type protein-coding
Description mesoderm posterior basic helix-loop-helix transcription factor 2
Other Description class C basic helix-loop-helix protein 6|mesoderm posterior 2 homolog|mesoderm posterior protein 2
Swissprots Q0VG99 Q7RTU2
Accessions DAA00304 Q0VG99 AL360139 BC111413 AAI11414 NM_001039958 NP_001035047
Function Transcription factor with important role in somitogenesis. Defines the rostrocaudal patterning of the somite by participating in distinct Notch pathways. Regulates also the FGF signaling pathway. Specifies the rostral half of the somites. Generates rostro-caudal polarity of somites by down-regulating in the presumptive rostral domain DLL1, a Notch ligand. Participates in the segment border formation by activating in the anterior presomitic mesoderm LFNG, a negative regulator of DLL1-Notch signaling. Acts as a strong suppressor of Notch activity. Together with MESP1 is involved in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981}.

MESP2 CRISPR/Cas9 KO Plasmid (h) - sc-407998 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MESP2 HDR Plasmid (h) - sc-407998-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MESP2 Double Nickase Plasmid (h) - sc-407998-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MESP2 Double Nickase Plasmid (h2) - sc-407998-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MESP2 CRISPR Activation Plasmid (h) - sc-407998-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MESP2 CRISPR Activation Plasmid (h2) - sc-407998-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MESP2 Lentiviral Activation Particles (h) - sc-407998-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MESP2 Lentiviral Activation Particles (h2) - sc-407998-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MESP2 siRNA (h) - sc-90260 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MESP2 shRNA Plasmid (h) - sc-90260-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MESP2 shRNA (h) Lentiviral Particles - sc-90260-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MESP2 RNAi - H00145873-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN13213 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13213 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MESP2 siRNA (Human) - CRJ5450 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MESP2 (NM_001039958.1) - SHH340523 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human MESP2(NM_001039958.1) - SHH185123 from Creative biogene

Category siRNA
Species Reactivities Human

Human MESP2 siRNA - orb275951 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MESP2 shRNA Plasmid (Human) - CHJ5450 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MESP2 miRNA 3'UTR clone - MiUTR1H-06212 from Creative biogene

Species Reactivities Human
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