CLPP

Gene Symbol CLPP
Entrez Gene 8192
Alt Symbol DFNB81, PRLTS3
Species Human
Gene Type protein-coding
Description caseinolytic mitochondrial matrix peptidase proteolytic subunit
Other Description ATP-dependent Clp protease proteolytic subunit, mitochondrial|ATP-dependent protease ClpAP, proteolytic subunit, human|ClpP caseinolytic peptidase ATP-dependent, proteolytic subunit|ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog|ClpP caseinolytic protease, ATP-dependent, proteolytic subunit homolog|endopeptidase Clp|putative ATP-dependent Clp protease proteolytic subunit, mitochondrial
Swissprots B2R4W5 Q16740
Accessions EAW69103 Q16740 AK311973 BAG34912 BC002956 AAH02956 BF339807 DQ895823 ABM86749 EF036491 ABO65077 EU176368 ABW03819 Z50853 CAA90705 NM_006012 NP_006003
Function Protease component of the Clp complex that cleaves peptides and various proteins in an ATP-dependent process. Has low peptidase activity in the absence of CLPX. The Clp complex can degrade CSN1S1, CSN2 and CSN3, as well as synthetic peptides (in vitro) and may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates. {ECO:0000269|PubMed:11923310, ECO:0000269|PubMed:15522782}.
Subcellular Location Mitochondrion matrix {ECO:0000269|PubMed:10525407}.
Tissue Specificity Detected in liver (at protein level). Predominantly expressed in skeletal muscle. Intermediate levels in heart, liver and pancreas. Low in brain, placenta, lung and kidney. {ECO:0000269|PubMed:10525407, ECO:0000269|PubMed:8543061}.

Human CLPP cDNA clone(NM_006012.2) - CDFH003883 from Creative Biomart

Species Human
Accession NM_006012.2

Human CLPP ORF Clone(NM_006012.2) - CDCL159120 from Creative Biomart

Species Human
Accession NM_006012.2

Human CLPP ORF Clone(NM_006012.2) - CDCR291816 from Creative Biomart

Species Human
Accession NM_006012.2

Human CLPP ORF Clone(NM_006012.2) - CDCR291817 from Creative Biomart

Species Human
Accession NM_006012.2

Human CLPP ORF clone(NM_006012.2) - CDCH383477 from Creative Biomart

Species Human
Accession NM_006012.2

Human CLPP ORF Clone(NM_006012.2) - CDCR291816 from Creative biogene

Species Human

Human CLPP cDNA Clone(NM_006012.2) - CDFH003883 from Creative biogene

Species Human
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