CLPP

Gene Symbol CLPP
Entrez Gene 8192
Alt Symbol DFNB81, PRLTS3
Species Human
Gene Type protein-coding
Description caseinolytic mitochondrial matrix peptidase proteolytic subunit
Other Description ATP-dependent Clp protease proteolytic subunit, mitochondrial|ATP-dependent protease ClpAP, proteolytic subunit, human|ClpP caseinolytic peptidase ATP-dependent, proteolytic subunit|ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog|ClpP caseinolytic protease, ATP-dependent, proteolytic subunit homolog|endopeptidase Clp|putative ATP-dependent Clp protease proteolytic subunit, mitochondrial
Swissprots B2R4W5 Q16740
Accessions EAW69103 Q16740 AK311973 BAG34912 BC002956 AAH02956 BF339807 DQ895823 ABM86749 EF036491 ABO65077 EU176368 ABW03819 Z50853 CAA90705 NM_006012 NP_006003
Function Protease component of the Clp complex that cleaves peptides and various proteins in an ATP-dependent process. Has low peptidase activity in the absence of CLPX. The Clp complex can degrade CSN1S1, CSN2 and CSN3, as well as synthetic peptides (in vitro) and may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates. {ECO:0000269|PubMed:11923310, ECO:0000269|PubMed:15522782}.
Subcellular Location Mitochondrion matrix {ECO:0000269|PubMed:10525407}.
Tissue Specificity Detected in liver (at protein level). Predominantly expressed in skeletal muscle. Intermediate levels in heart, liver and pancreas. Low in brain, placenta, lung and kidney. {ECO:0000269|PubMed:10525407, ECO:0000269|PubMed:8543061}.

CLPP Antibody - 14181 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using CLPP Antibody.

ClpP (B-12) - sc-271284 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ClpP (B-12): sc-271284. Western blot analysis of ClpP expression in non-transfected: sc-117752 (A) and mouse ClpP transfected: sc-119316 (B) 293T whole cell lysates.

ClpP (C-17) - sc-47845 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ClpP (C-17): sc-47845. Western blot analysis of ClpP expression in non-transfected: sc-117752 (A) and mouse ClpP transfected: sc-119316 (B) 293T whole cell lysates.

ClpP (FL-277) - sc-134496 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ClpP (FL-277): sc-134496. Western blot analysis of ClpP expression in non-transfected 293T: sc-117752 (A), mouse ClpP transfected 293T: sc-119316 (B), Saos-2 (D) and A-431 (E) whole cell lysates and mouse heart tissue extract (F).

ClpP (E-19) - sc-47846 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ClpP (E-19): sc-47846. Western blot analysis of ClpP expression in mouse heart tissue extract.

ClpP (P-15) - sc-47847 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ClpP (P-15): sc-47847. Western blot analysis of ClpP expression in non-transfected: sc-117752 (A) and mouse ClpP transfected: sc-119316 (B) 293T whole cell lysates.

ClpP (Q-20) - sc-47848 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ClpP (Q-20): sc-47848. Western blot analysis of ClpP expression in non-transfected: sc-117752 (A) and mouse ClpP transfected: sc-119316 (B) 293T whole cell lysates.

Anti-CLPP antibody - ab56455 from Abcam

Prices $378.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-CLPP antibody - ab126102 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-CLPP antibody (ab126102) at 1/1000 dilution + Jurkat whole cell lysate at 30 µg

Anti-CLPP antibody - ab15708 from Abcam

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Immunohistochemical analysis of paraffin embedded Human liver tissue labeling CLPP with ab15708 at 2 ug/ml. Tissue underwent antigen retrieval in steam with citrate buffer (pH 6.0) and HRP staining.

Anti-CLPP antibody - ab96672 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CLPP antibody (ab96672) at 1/1500 dilutionLane 1 : 293T whole cell lysateLane 2 : A431 whole cell lysateLane 3 : H1299 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-CLPP antibody [1E2] - ab119065 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1E2
HEK293T cells transfected with either overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained with ab119065 at 1/100, and then analyzed by flow cytometry.

Anti-CLPP antibody [EPR7133] - ab124822 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7133
All lanes : Anti-CLPP antibody [EPR7133] (ab124822) at 1/1000 dilutionLane 1 : Fetal muscle lysateLane 2 : Saos-2 cell lysateLane 3 : A431 cell lysateLane 4 : 293T cell lysateLane 5 : K562 cell lysateLane 6 : A549 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-CLPP Antibody (aa178-278, clone 10B2264, Azide-free) - LS-C183522 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 10B2264

Anti-CLPP Antibody (aa196-245) - LS-C151516 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
CLPP antibody Western Blot of 293T.

Anti-CLPP Antibody (Internal, clone EPR7133) - LS-C138964 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7133
Western blot analysis on (A) fetal muscle, (B) Saos-2, (C) A431, (D) 293T, (E) K562, and (F) A549 lysates using anti-CLPP antibody.

Anti-CLPP Antibody (clone 1D8) - LS-C115827 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1D8
Anti-CLPP mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CLPP.

Anti-CLPP Antibody (clone 1E2) - LS-C337161 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1E2
IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-CLPP mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).

Anti-CLPP Antibody (clone 1C7) - LS-C172469 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1C7
IHC of paraffin-embedded Human pancreas tissue using anti-CLPP mouse monoclonal antibody.

Anti-CLPP Antibody (clone 1G9) - LS-C172470 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1G9
IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-CLPP mouse monoclonal antibody.

Anti-CLPP Antibody (clone 1F6) - LS-C172471 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1F6
IHC of paraffin-embedded Carcinoma of Human pancreas tissue using anti-CLPP mouse monoclonal antibody.

Anti-CLPP Antibody - LS-C155399 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded Colon ca, using CLPP antibody at 1:250 dilution.

Anti-CLPP Antibody (clone 3E2) - LS-C133541 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3E2
Immunoperoxidase of monoclonal antibody to CLPP on formalin-fixed paraffin-embedded human kidney. [antibody concentration 1 ug/ml]

Anti-CLPP Antibody (C-Terminus) IHC-plus™ - LS-B2749 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-CLPP antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2749 concentration 5 ug/ml.

Anti-CLPP Antibody (aa215-277) IHC-plus™ - LS-B12082 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
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