WIPI2

Gene Symbol	WIPI2
Entrez Gene	26100
Alt Symbol	ATG18B, Atg21, CGI-50, WIPI-2
Species	Human
Gene Type	protein-coding
Description	WD repeat domain, phosphoinositide interacting 2
Other Description	WD repeat domain phosphoinositide-interacting protein 2|WD40 repeat protein interacting with phosphoinositides 2|WIPI49-like protein 2
Swissprots	Q9Y4P8 Q9Y364 B3KNC2 Q5MNZ8 Q96IE4 Q75L50 Q6FI96
Accessions	AAQ96865 AAQ96866 AAQ96867 EAW87324 EAW87325 EAW87326 EAW87327 EAW87328 Q9Y4P8 AF151808 AAD34045 AI074985 AK023041 BAG51152 AK024279 BAG51284 AK124974 BAC86012 AK125007 AK315468 AL080155 CAB45746 AM392901 CAL37779 AM393618 CAL38494 AM393628 CAL38504 AY691425 AAV80761 AY691426 AAV80762 BC004116 AAH04116 BC007596 AAH07596 BC016912 BC021012 BC021068 BC021200 AAH21200 BI561383 BX537624 CAH56163 CR533530 CAG38561 XM_006715685 XP_006715748 NM_001033518 NP_001028690 NM_001033519 NP_001028691 NM_001033520 NP_001028692 NM_001278299 NP_001265228 NM_015610 NP_056425 NM_016003 NP_057087
Function	Early component of the autophagy machinery being involved in formation of preautophagosomal structures and their maturation into mature phagosomes in response to phosphatidylinositol 3-phosphate (PtdIns3P). May bind PtdIns3P. {ECO:0000269|PubMed:20505359}.
Subcellular Location	Preautophagosomal structure membrane {ECO:0000269|PubMed:20505359, ECO:0000269|PubMed:21564513, ECO:0000269|PubMed:22456507, ECO:0000269|PubMed:23916833}; Peripheral membrane protein {ECO:0000269|PubMed:20505359, ECO:0000269|PubMed:21564513, ECO:0000269|PubMed:22456507}; Cytoplasmic side {ECO:0000269|PubMed:20505359, ECO:0000269|PubMed:21564513, ECO:0000269|PubMed:22456507}. Note=Localizes to omegasomes membranes which are endoplasmic reticulum connected strutures at the origin of preautophagosomal structures. Enriched at preautophagosomal structure membranes in response to PtdIns3P. {ECO:0000269|PubMed:24954904}.
Tissue Specificity	Ubiquitously expressed (at protein level). Highly expressed in heart, skeletal muscle and pancreas. Expression is down-regulated in pancreatic and in kidney tumors. {ECO:0000269|PubMed:15602573, ECO:0000269|PubMed:20505359}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human WIPI2 full length protein - ab153266 from Abcam Category Protein Source Wheat germ Species Human

WIPI2 Antibody Blocking Peptide - LS-E2350 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

WIPI2 Antibody Blocking Peptide - LS-E31362 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

WIPI2 Antibody Blocking Peptide - LS-E10194 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

WIPI2 Recombinant Protein - H00026100-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

WIPI2-Antibody-N-term-Blocking-peptide - BP13314a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

WIPI2-Antibody-C-term-Blocking-Peptide - BP9559b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

WIPI-2 - H00026100-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

WIPI-2 - H00026100-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

WIPI-2 (N-term) Control Peptide - AP55522CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

WIPI2 Peptide - 7103P from ProSci Category Peptide Species Human

WIPI2 fusion protein - ag7689 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

WIPI2 fusion protein - ag8147 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human WD repeat domain phosphoinositide-interacting protein 2(WIPI2) - CSB-YP896519HU CSB-EP896519HU CSB-BP896519HU CSB-MP896519HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

WIPI2 Protein - abx164417 from Abbexa Category Protein Species Human, Mouse, Rat

WD repeat domain phosphoinositide-interacting protein 2 (WIPI2) , Recombinant Protein - MBS1391299 from MyBioSource Category Protein Prices $2,005.00, $2,005.00, $2,470.00, $2,470.00 Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

WIPI2 Recombinant Protein Antigen - NBP1-88880PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

WIPI2 Recombinant Protein Antigen - NBP1-88879PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

WIPI2 Peptide, Human - M34GP17501H from Creative Peptides Category Peptide Source Synthetic. Species Human

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