MCM10

Gene Symbol MCM10
Entrez Gene 55388
Alt Symbol CNA43, DNA43, PRO2249
Species Human
Gene Type protein-coding
Description minichromosome maintenance complex component 10
Other Description MCM10 minichromosome maintenance deficient 10|homolog of yeast MCM10|hsMCM10|protein MCM10 homolog
Swissprots Q7L590 Q96GX4 Q3MIR3 A8K9I6 Q9H3P9 Q96NB6 B7ZKZ8 Q7LD55 Q9P177 Q9H0D7
Accessions AAB34309 AAB34784 EAW86297 EAW86298 Q7L590 AB042719 BAB18723 AF119869 AAF69623 AK055695 BAB70988 AK292701 BAF85390 AL136840 CAB66774 BC004876 AAH04876 BC009108 BC101727 AAI01728 BC143490 AAI43491 DA024424 XM_011519538 XP_011517840 NM_018518 NP_060988 NM_182751 NP_877428
Function Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication. Additionally, plays a role in preventing DNA damage during replication. {ECO:0000269|PubMed:11095689, ECO:0000269|PubMed:15136575, ECO:0000269|PubMed:17699597, ECO:0000269|PubMed:19608746}.
Subcellular Location Nucleus {ECO:0000269|PubMed:11095689, ECO:0000269|PubMed:15136575}. Note=Colocalizes with ORC2 in nuclei foci. Associated with chromatin in S phase. From early to mid-S phase located in discrete nuclear foci. In early S phase, several hundred foci appeared throughout the nucleus. In mid-S phase, the foci appeared at the nuclear periphery and nucleolar regions. In the late S and G phases localized to nucleoli.

MCM10 (C-16) - sc-47111 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MCM10 (C-16): sc-47111. Immunofluorescence staining of formalin-fixed HeLa cells showing cytoplasmic and nuclear localization. Kindly provided by Yang Xiang, Ph.D., Division of Newborn Medicine, Boston Childrens Hospital, Cell Biology Department, Harvard Medical School.

MCM10 (C-14) - sc-47110 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MCM10 (H-41) - sc-99037 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-MCM10 antibody - ab3733 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-MCM10 antibody - ab116072 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-MCM10 antibody (ab116072) at 1 µg/ml + Mouse pancreas lysate at 10 µg

Anti-MCM10 Antibody - LS-C72302 from LifeSpan Bioscience

Prices $575.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MCM10 Antibody - LS-C310962 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MCM10 Antibody - LS-C334056 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of HepG2 cell line, using MCM10 antibody.

Anti-MCM10 Antibody (aa40-89) - LS-C145321 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MCM10 antibody LS-C145321 Western blot of Mouse Pancreas lysate. Antibody concentration 1 ug/ml.

Anti-MCM10 Antibody - LS-C346276 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence blot of A549 cell using MCM10 antibody. Blue: DAPI for nuclear staining.

Anti-MCM10 Antibody (aa648-697) - LS-C110187 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MCM10 antibody LS-C110187 Western blot of Jurkat lysate.

Anti-MCM10 Antibody (aa600-650) - LS-C287058 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human MCM10 by Western Blot following Immunoprecipitation. Sample: HeLa cell lysate (1 mg for IP). Similar results were obtained with HCT116 cells (not shown). Antibody: Affinity purified rabbit anti-MCM10 used at 1 ug/mg lysate for IP and 0.5 ug/ml for WB. Detection: Chemiluminescence.

MCM10 Antibody - NB100-253 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MCM10 Antibody [NB100-253] - Detection of Human MCM10 on HeLa whole cell lysate using NB100-253.

MCM10 Antibody - NBP1-92102 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: MCM10 Antibody [NBP1-92102] - Staining of human esophagus shows strong cytoplasmic and nuclear positivity in superficial layers of squamous epithelial cells.

MCM10 Antibody - H00055388-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: MCM10 Antibody [H00055388-B01P] - Analysis of MCM10 expression in transfected 293T cell line by MCM10 polyclonal antibody. Lane 1: MCM10 transfected lysate(96.14 KDa). Lane 2: Non-transfected lysate.

MCM10 Antibody - H00055388-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: MCM10 Antibody [H00055388-D01P] - Analysis of MCM10 expression in transfected 293T cell line by MCM10 polyclonal antibody.Lane 1: MCM10 transfected lysate(98.10 KDa).Lane 2: Non-transfected lysate.

Anti-MCM10 antibody produced in rabbit - SAB2101443 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-MCM10: <B>Cat. No.SAB2101443</B>: MCM10 in Jurkat cell lysate with MCM10 antibody at 1.0 μg/mL.

Anti-MCM10 antibody produced in rabbit - HPA045899 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MCM10: <B>Cat. No. HPA045899</B>: Immunohistochemical staining of human esophagus shows strong cytoplasmic and nuclear positivity in superficial layers of squamous epithelial cells.

Anti-MCM10 antibody produced in mouse - SAB1409496 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-MCM10: <B>Cat. No. SAB1409496</B>: Antibody concentration: 10 μg/mL using HeLa cell.

Anti-MCM10 antibody produced in rabbit - SAB1411058 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-MCM10: <B>Cat. No. SAB1411058</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~98.1 kDa using MCM10 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

MCM10 antibody - middle region (ARP36656_P050) - ARP36656_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

MCM10 antibody, Internal - GTX47473 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal

MCM10 antibody - 70R-5512 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti -MCM10 (Mini Chromosome Maintenance Protein 10, CNA43, DNA43, PRO2249) - 211939 from USBiological Life Science

Host Rabbit
Clonality Polyclonal
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