MCM10
| Gene Symbol | MCM10 |
|---|---|
| Entrez Gene | 55388 |
| Alt Symbol | CNA43, DNA43, PRO2249 |
| Species | Human |
| Gene Type | protein-coding |
| Description | minichromosome maintenance complex component 10 |
| Other Description | MCM10 minichromosome maintenance deficient 10|homolog of yeast MCM10|hsMCM10|protein MCM10 homolog |
| Swissprots | Q7L590 Q96GX4 Q3MIR3 A8K9I6 Q9H3P9 Q96NB6 B7ZKZ8 Q7LD55 Q9P177 Q9H0D7 |
| Accessions | AAB34309 AAB34784 EAW86297 EAW86298 Q7L590 AB042719 BAB18723 AF119869 AAF69623 AK055695 BAB70988 AK292701 BAF85390 AL136840 CAB66774 BC004876 AAH04876 BC009108 BC101727 AAI01728 BC143490 AAI43491 DA024424 XM_011519538 XP_011517840 NM_018518 NP_060988 NM_182751 NP_877428 |
| Function | Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication. Additionally, plays a role in preventing DNA damage during replication. {ECO:0000269|PubMed:11095689, ECO:0000269|PubMed:15136575, ECO:0000269|PubMed:17699597, ECO:0000269|PubMed:19608746}. |
| Subcellular Location | Nucleus {ECO:0000269|PubMed:11095689, ECO:0000269|PubMed:15136575}. Note=Colocalizes with ORC2 in nuclei foci. Associated with chromatin in S phase. From early to mid-S phase located in discrete nuclear foci. In early S phase, several hundred foci appeared throughout the nucleus. In mid-S phase, the foci appeared at the nuclear periphery and nucleolar regions. In the late S and G phases localized to nucleoli. |
Human MCM10 full length protein - ab153397 from Abcam
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MCM10 Antibody Blocking Peptide - LS-E13146 from LifeSpan Bioscience
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MCM10 Antibody Blocking Peptide - LS-E13151 from LifeSpan Bioscience
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MCM10 Recombinant Protein - H00055388-P01 from Novus Biologicals
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MCM10 Blocking Peptide - 33R-7173 from Fitzgerald
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Mcm10 Blocking Peptide - 33R-1899 from Fitzgerald
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MCM10 - H00055388-P01 from Acris Antibodies
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MCM10 fusion protein - ag2899 from Proteintech Group
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Recombinant Human Protein MCM10 homolog(MCM10) ,partial - CSB-YP745335HU CSB-EP745335HU CSB-BP745335HU CSB-MP745335HU from Cusabio
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MCM10 Recombinant Protein Antigen - NBP1-92102PEP from Novus Biologicals
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MCM10 Peptide, Human - M34GP09312H from Creative Peptides
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MCM10 Recombinant Protein Antigen - NBP2-57966PEP from Novus Biologicals
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Protein MCM10 homolog (MCM10), partial, Recombinant Protein - MBS1411925 from MyBioSource
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