MCM10

Gene Symbol MCM10
Entrez Gene 55388
Alt Symbol CNA43, DNA43, PRO2249
Species Human
Gene Type protein-coding
Description minichromosome maintenance complex component 10
Other Description MCM10 minichromosome maintenance deficient 10|homolog of yeast MCM10|hsMCM10|protein MCM10 homolog
Swissprots Q7L590 Q96GX4 Q3MIR3 A8K9I6 Q9H3P9 Q96NB6 B7ZKZ8 Q7LD55 Q9P177 Q9H0D7
Accessions AAB34309 AAB34784 EAW86297 EAW86298 Q7L590 AB042719 BAB18723 AF119869 AAF69623 AK055695 BAB70988 AK292701 BAF85390 AL136840 CAB66774 BC004876 AAH04876 BC009108 BC101727 AAI01728 BC143490 AAI43491 DA024424 XM_011519538 XP_011517840 NM_018518 NP_060988 NM_182751 NP_877428
Function Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication. Additionally, plays a role in preventing DNA damage during replication. {ECO:0000269|PubMed:11095689, ECO:0000269|PubMed:15136575, ECO:0000269|PubMed:17699597, ECO:0000269|PubMed:19608746}.
Subcellular Location Nucleus {ECO:0000269|PubMed:11095689, ECO:0000269|PubMed:15136575}. Note=Colocalizes with ORC2 in nuclei foci. Associated with chromatin in S phase. From early to mid-S phase located in discrete nuclear foci. In early S phase, several hundred foci appeared throughout the nucleus. In mid-S phase, the foci appeared at the nuclear periphery and nucleolar regions. In the late S and G phases localized to nucleoli.

MCM10 CRISPR/Cas9 KO Plasmid (h) - sc-407631 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM10 HDR Plasmid (h) - sc-407631-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM10 Double Nickase Plasmid (h) - sc-407631-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM10 Double Nickase Plasmid (h2) - sc-407631-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM10 CRISPR Activation Plasmid (h) - sc-407631-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM10 CRISPR Activation Plasmid (h2) - sc-407631-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM10 Lentiviral Activation Particles (h) - sc-407631-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM10 Lentiviral Activation Particles (h2) - sc-407631-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM10 siRNA (h) - sc-61000 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MCM10 shRNA Plasmid (h) - sc-61000-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MCM10 shRNA (h) Lentiviral Particles - sc-61000-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU157051 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN13116 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13116 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MCM10 siRNA (Human) - CRJ0696 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MCM10 (NM_182751.2) - SHH339263 from Creative biogene

Category siRNA
Species Reactivities Human

Human MCM10 siRNA - orb271197 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MCM10 shRNA Plasmid (Human) - CHJ0696 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MCM10 miRNA 3'UTR clone - MiUTR3H-10555 from Creative biogene

Species Reactivities Human

MCM10 miRNA 3'UTR clone - MiUTR3H-10556 from Creative biogene

Species Reactivities Human
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