ZFAT

Gene Symbol ZFAT
Entrez Gene 57623
Alt Symbol AITD3, ZFAT1, ZNF406
Species Human
Gene Type protein-coding
Description zinc finger and AT hook domain containing
Other Description zinc finger gene in autoimmune thyroid disease|zinc finger protein 406|zinc finger protein ZFAT|zinc-finger gene in AITD susceptibility region
Swissprots Q75PJ9 Q3MIM5 Q9P243 Q86X64 E9PER3 Q6PJ01 B7ZL15 Q75PJ6 Q75PJ7
Accessions EAW92179 Q9P243 AB040918 BAA96009 AB167738 BAD12567 AB167739 BAD12568 AB167740 BAD12569 AB167741 BAD12570 AK094089 AK300133 BAH13220 AK300324 BAH13257 AK300471 BAH13290 AK301413 BAH13477 AK311494 AL832066 BC012989 AAH12989 BC025423 AAH25423 BC039059 BC046180 AAH46180 BC070097 BC098405 AAH98405 BC101766 AAI01767 BC101768 AAI01769 BC143519 AAI43520 BI964061 BM685256 DC333809 XM_011517203 XP_011515505 XM_011517204 XP_011515506 XM_011517205 XP_011515507 XM_011517206 XP_011515508 XR_928343 NM_001029939 NP_001025110 NM_001167583 NP_001161055 NM_001174157 NP_001167628 NM_001174158 NP_001167629 NM_001289394 NP_001276323 NM_020863 NP_065914 NR_110323
Function May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}.
Tissue Specificity Isoform 1 is strongly expressed in placenta, spleen, kidney, testis and peripheral blood leukocytes. Expressed in CD4+ and CD8+ T-cells, CD19+ B-cells and CB14+ monocytes. Isoform 3 is strongly expressed in placenta, ovary, tonsil, CD19+ B-cells and CD14+ monocytes. {ECO:0000269|PubMed:15294872}.

ZFAT (E-9) - sc-398058 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ZFAT (E-9): sc-398058. Western blot analysis of ZFAT expression in LADMAC (A), Raji (B), Jurkat (C), NTERA-2 cl.D1 (D), Hs 181 Tes (E) and HeLa (F) whole cell lysates.

ZFAT (E-14) - sc-87509 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ZFAT (H-275) - sc-367786 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ZFAT (H-275): sc-367786. Western blot analysis of ZFAT expression in Jurkat (A), Raji (B), NTERA-2 cl.D1 (C), DU 145 (D), Hs 181 Tes (E) and HeLa (F) whole cell lysates.

ZFAT (N-17) - sc-87510 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ZFAT (N-17): sc-87510. Western blot analysis of ZFAT expression in LADMAC whole cell lysate.

Anti-ZFAT antibody - ab154722 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ZFAT antibody (ab154722) at 1/1000 dilutionLane 1 : Jurkat whole cell lysateLane 2 : Raji whole cell lysateLysates/proteins at 30 µg per lane.

Anti-ZFAT Antibody (aa359-408) - LS-C101420 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ZFAT antibody LS-C101420 Western blot of Fetal Muscle lysate.

ZNF406 Antibody - NBP2-13542 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: ZNF406 Antibody [NBP2-13542] - Staining of human placenta shows strong nuclear positivity in trophoblastic cells.

ZNF406 Antibody - NBP2-21005 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ZNF406 Antibody [NBP2-21005] - Sample (30 ug of whole cell lysate) A: Jurkat B: Raji 5% SDS PAGE gel, diluted at 1:1000.

Anti-ZFAT antibody produced in rabbit - SAB2700708 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ZFAT: <B>Cat. No. SAB2700708</B>: Immunohistochemical analysis of paraffin-embedded HBL435 xenograft, using ZFAT antibody at 1:500 dilution.

Anti-ZFAT1 antibody produced in rabbit - SAB2102764 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ZFAT1: <B>Cat. No.SAB2102764</B>: ZFAT1 in Fetal Muscle tissue lysate with ZFAT1 antibody at 1.0 μg/mL.

ZFAT1 antibody - middle region (ARP32966_P050) - ARP32966_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ZFAT1 Antibody - 25-105 from ProSci

Prices $315.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Antibody used in WB on Human Muscle at 0.2-1 ug/ml.

ZFAT1 Antibody - GWB-ML469A from Genway Biotech

Prices $404.00
Sizes 50 µg
Clonality Polyclonal

Anti-ZFAT (aa 825-1083) polyclonal antibody - DPABH-04670 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

Anti-ZFAT (aa 360-409) polyclonal antibody - DPABH-18759 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

ZFAT Polyclonal Antibody - PA5-32037 from Thermo Fisher Scientific

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent analysis of ZFAT showing staining in the nucleus of SKNSH cells. SKNSH cells were fixed in 4% paraformaldehyde at RT for 15 min and stained using a ZFAT polyclonal antibody (Product # PA5-32037) diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 ?m.

ZFAT - MBS273132 from MyBioSource

Prices $360.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate) A: Jurkat B: Raji 5% SDS PAGE diluted at 1:1000

ZFAT1-antibody-middle-region-AI10444 - AI10444 from Abgent, a WuXi AppTec company

Prices $293.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
WB Suggested Anti-ZFAT1 Antibody Titration: .2-1 ug/ml ELISA Titer: 1:3125 Positive Control: Human Muscle

PCRP-ZFAT-2D2 - PCRP-ZFAT-2D2 from Developmental Studies Hybridoma Bank

Host Mouse
Clonality Monoclonal

Anti-ZFAT antibody produced in rabbit - HPA020989 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ZFAT:<B>Cat. No. HPA020989</B>: Immunohistochemical staining of human placenta shows strong nuclear positivity in trophoblastic cells.

ZNF406 antibody - TA332158 from Acris Antibodies

Prices $325.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
WB Suggested Anti-ZFAT1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Human Muscle

ZFAT1 antibody - middle region : Biotin (ARP32966_P050-Biotin) - ARP32966_P050-Biotin from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ZFAT1 antibody - middle region : FITC (ARP32966_P050-FITC) - ARP32966_P050-FITC from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ZFAT1 antibody - middle region : HRP (ARP32966_P050-HRP) - ARP32966_P050-HRP from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ZFAT1 Antibody A11438 - A11438 from Boster Bio

Prices $299.00
Sizes 1
Host Rabbit
Clonality Polyclonal
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