UNC5A

Gene Symbol	UNC5A
Entrez Gene	90249
Alt Symbol	UNC5H1
Species	Human
Gene Type	protein-coding
Description	unc-5 homolog A (C. elegans)
Other Description	netrin receptor UNC5A|netrin receptor Unc5h1|protein unc-5 homolog 1|protein unc-5 homolog A|unc-5 homolog 1|unc5 (C.elegans homolog) a
Swissprots	B2RXE6 Q96GP4 Q8TF26 Q6ZN44
Accessions	EAW85050 EAW85051 EAW85052 Q6ZN44 AB075856 BAB85562 AK131380 BAD18531 BC009333 AAH09333 BC033727 AAH33727 BC122556 AAI22557 BC157824 AAI57825 BC167811 AAI67811 BI818609 BM712478 XM_006714927 XP_006714990 XM_006714928 XP_006714991 XM_011534686 XP_011532988 XM_011534687 XP_011532989 NM_133369 NP_588610
Function	Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.
Subcellular Location	Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=The interaction with PRKCABP regulates its surface expression and leads to its removal from surface of neurons and growth cones. {ECO:0000250}.
Top Pathways	Axon guidance

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Unc5a peptide - ab26987 from Abcam Category Peptide

Rat Unc5a peptide - ab39652 from Abcam Category Peptide

Rat Unc5a peptide - ab39653 from Abcam Category Peptide

Recombinant Human UNC5H1/Unc5a Protein - H00090249-G01-10ug from Novus Biologicals Category Protein Prices $569.00 Sizes 10 µg Species Human

Recombinant Human UNC5H1 Fc Chimera, CF - 6767-UN-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Human UNC5A (Fc Tag) protein - orb232305 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Species Human

Human UNC5A (His Tag) protein - orb232306 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Species Human

UNC5A Blocking Peptide - 33R-9915 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

UNC5A Blocking Peptide - abx161235 from Abbexa Category Peptide Species Human, Mouse, Rat

UNC5A fusion protein - ag16221 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

UNC5A fusion protein - ag17155 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human UNC5A, Fc Chimera - UNC5A-811H from Creative Biomart Category Protein Source NSO Cells Species Human

Recombinant Human Unc-5 Homolog A (C. Elegans), Fc Chimera - UNC5A-2437H from Creative Biomart Category Protein Source CHO cells.

Human UNC5A / UNC5H1 Protein (ECD, Fc Tag) - 13424-H02H-100 from Sino Biological Category Protein Prices $298.00, $298.00 Sizes 50 µg, 100 µg Source Human Cells Species Human

Human UNC5A / UNC5H1 Protein (ECD, His Tag) - 13424-H08H-100 from Sino Biological Category Protein Prices $298.00, $298.00 Sizes 50 µg, 100 µg Source Human Cells Species Human

UNC5A Blocking Peptide - CBP3734 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

Recombinant Human Netrin receptor UNC5A(UNC5A) - CSB-YP754541HU CSB-EP754541HU CSB-BP754541HU CSB-MP754541HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human UNC5H1 Fc Chimera Protein, CF - 6767-UN from R&D Systems Category Protein Prices $329.00 Sizes 50 µg Source Mouse myeloma cell line, NS0-derived Human UNC5H1 (Gln26 - Tyr306) Accession # NP_588610 IEGRMD Human IgG 1 (Pro100 - Lys330) N-terminus C-terminus Species Human

UNC5A - TP312389 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Recombinant Human UNC5A Protein, Fc-tagged - UNC5A-533H from Creative Biomart Category Protein Source HEK293 Species Human

Recombinant Human UNC5A Protein, His-tagged - UNC5A-534H from Creative Biomart Category Protein Source HEK293 Species Human

UNC5A Peptide, Human - M34GP17091H from Creative Peptides Category Peptide Source Synthetic. Species Human

Human UNC5A / UNC5H1 Protein (ECD, Fc Tag) - 13424-H02H from ABclonal Category Protein Prices $178.00, $298.00 Sizes 50 µg, 100 µg Source Human Cells Species Human

Human UNC5A / UNC5H1 Protein (ECD, His Tag) - 13424-H08H from ABclonal Category Protein Prices $178.00, $298.00 Sizes 50 µg, 100 µg Source Human Cells Species Human

UNC5H1/Unc5a Recombinant Protein Antigen - NBP2-57451PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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