EPHB1

Gene Symbol	EPHB1
Entrez Gene	2047
Alt Symbol	ELK, EPHT2, Hek6, NET
Species	Human
Gene Type	protein-coding
Description	EPH receptor B1
Other Description	EK6|EPH-like kinase 6|eph tyrosine kinase 2|ephrin type-B receptor 1|neuronally-expressed EPH-related tyrosine kinase|soluble EPHB1 variant 1|tyrosine-protein kinase receptor EPH-2
Swissprots	O95143 Q0VG87 O43569 P54762 B3KTB2 A8K593 B5A969 O95142
Accessions	CAT16944 CCF76954 EAW79127 EAW79128 EAW79129 P54762 AF037333 AAB94627 AF037334 AAB94628 AK095305 BAG53024 AK291208 BAF83897 AK309741 AW207121 BC111744 AAI11745 BM665724 DA107464 EU826607 ACF47643 L40636 AAB08520 XM_011512540 XP_011510842 XM_011512541 XP_011510843 XM_011512542 XP_011510844 NM_004441 NP_004432
Function	Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Cognate/functional ephrin ligands for this receptor include EFNB1, EFNB2 and EFNB3. During nervous system development, regulates retinal axon guidance redirecting ipsilaterally ventrotemporal retinal ganglion cells axons at the optic chiasm midline. This probably requires repulsive interaction with EFNB2. In the adult nervous system together with EFNB3, regulates chemotaxis, proliferation and polarity of the hippocampus neural progenitors. In addition to its role in axon guidance plays also an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and synapse formatio
Subcellular Location	Cell membrane {ECO:0000269|PubMed:18034775}; Single-pass type I membrane protein {ECO:0000269|PubMed:18034775}. Early endosome membrane {ECO:0000269|PubMed:18034775}. Cell projection, dendrite {ECO:0000250}.
Tissue Specificity	Preferentially expressed in brain.
Top Pathways	Axon guidance

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse/Human EPHB1 / EPH Receptor B1 ELISA Kit (Cell-Based ELISA) - LS-F1968 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate

Phosphotyrosine EPHB1 / Ephrin Type-B Receptor 1 ELISA Kit - RAB0949 from Sigma-Aldrich Category ELISA Kit Prices $637.00 Sizes 1 kt

EPH receptor B1, ELISA Kit - MBS918842 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human EPHB1 is typically less than 15.6 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 62.5 pg/ml -4000 pg/ml.

EPHB1/2 Colorimetric Cell-Based ELISA Kit - CB5238 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

EPHB1/2/3/4 Colorimetric Cell-Based ELISA Kit - CB5239 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

EPHB1/2 (Phospho-Tyr594/604) Colorimetric Cell-Based ELISA Kit - CBP1366 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

Human Ephrin type-B receptor 1(EPHB1) ELISA kit - CSB-EL007729HU from Cusabio Category ELISA Kit Sensitivity 15.6 pg/ml. Range 62.5 pg/ml-4000 pg/ml

EPHB1/2 ELISA Kit - DEIA-XYA602 from Creative Diagnostics Category ELISA Kit

EPHB1/2/3/4 ELISA Kit - DEIA-XYA604 from Creative Diagnostics Category ELISA Kit

EPHB1/2 (Phospho-Tyr594/604) ELISA Kit - DEIA-XYA603 from Creative Diagnostics Category ELISA Kit

Human Ephrin type-B receptor 1 (EPHB1) ELISA Kit - EKC33586 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,288.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 15.6 pg/ml Range 62.5 pg/ml-4000 pg/ml

Custom Human Phosphotyrosine EphB1 ELISA - PEL-EPHB1-Y-1 from RayBiotech Category ELISA Kit Prices $627.00, $1,128.60, $2,508.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human EPHB1 ELISA Kit - E013300 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of human EPHB1 is typically less than 15.6 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the me

anti-EphB1 antibody - ARG54851 from Arigo Biolaboratories Category ELISA Kit

EPHB1 ELISA Kit (Human) (OKCA01224) - OKCA01224 from Aviva Systems Biology Category ELISA Kit Prices $600.00 Sizes 96 wells Sensitivity 15.6 pg/mL Range 62.5 - 4,000 pg/mL

Human EPHB1 ELISA Kit - orb404374 from Biorbyt Category ELISA Kit Sensitivity 15.6 pg/ml. Range 62.5 pg/ml-4000 pg/ml

EPHB1/2 Colorimetric Cell-Based ELISA Kit - EKA50202 from Biomatik Category ELISA Kit Prices $399.00 Sizes 96 tests Sensitivity At least 5000 cells/well Range Qualitative

EPHB1/2/3/4 Colorimetric Cell-Based ELISA Kit - EKA50203 from Biomatik Category ELISA Kit Prices $399.00 Sizes 96 tests Sensitivity At least 5000 cells/well Range Qualitative

Phospho-EPHB1/2 (Tyr594/604) Colorimetric Cell-Based ELISA Kit - EKA51294 from Biomatik Category ELISA Kit Prices $504.00 Sizes 192 tests Sensitivity At least 5000 cells/well Range Qualitative

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