LZTS2

Gene Symbol	LZTS2
Entrez Gene	84445
Alt Symbol	LAPSER1
Species	Human
Gene Type	protein-coding
Description	leucine zipper, putative tumor suppressor 2
Other Description	hLZTS2|leucine zipper putative tumor suppressor 2|protein LAPSER1
Swissprots	Q8N3I0 D3DR72 Q96JL2 Q96J79 B1AL14 Q9BRK4
Accessions	EAW49790 EAW49791 EAW49792 Q9BRK4 AB058716 BAB47442 AK097997 AK298208 BAG60478 AL834338 CAD39005 AY029201 AAK31577 BC005855 AAH05855 BC006212 AAH06212 BC058938 AAH58938 BM544815 CB243010 XM_005270222 XP_005270279 XM_005270223 XP_005270280 XM_005270224 XP_005270281 XM_006718032 XP_006718095 NM_032429 NP_115805
Function	Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. {ECO:0000255|HAMAP-Rule:MF_03026, ECO:0000269|PubMed:17000760, ECO:0000269|PubMed:17351128, ECO:0000269|PubMed:17950943, ECO:0000269|PubMed:18490357}.
Subcellular Location	Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localized to the centrosome throughout the cell cycle. Localized to the midbody in cells undergoing cytokinesis.
Tissue Specificity	Highly expressed in prostate and testis, and at slightly lower levels in spleen, thymus, uterus, small intestine and colon. {ECO:0000269|PubMed:11709705}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human LZTS2 full length protein - ab164592 from Abcam Category Protein Source Wheat germ Species Human

Human LZTS2 protein fragment - ab164593 from Abcam Category Protein Source Wheat germ Species Human

LZTS2 Antibody Blocking Peptide - LS-E2105 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LZTS2 Antibody Blocking Peptide - LS-E21523 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LZTS2 Antibody Blocking Peptide - LS-E30663 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

LZTS2 Antibody Blocking Peptide - LS-E31213 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human LZTS2 Protein - H00084445-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

LZTS2 Partial Recombinant Protein - H00084445-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

LZTS2-Antibody-C-term-Blocking-peptide - BP13002b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

LZTS2 Blocking Peptide - 33R-2636 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

LZTS2 - H00084445-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

LZTS2 - H00084445-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

LZTS2 - H00084445-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

LZTS2 (N-term) Control Peptide - AP55605CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

LZTS2 (C-term) Control Peptide - AP55656CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

LZTS2 Peptide - 5073P from ProSci Category Peptide Species Human

LZTS2 Peptide - 6635P from ProSci Category Peptide Species Human

LZTS2 fusion protein - ag8145 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

LZTS2 fusion protein - ag9393 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

LZTS2 fusion protein - ag9690 from Proteintech Group Category Protein Source E. coli-derived, Species Human

Recombinant Human Leucine zipper putative tumor suppressor 2(LZTS2) - CSB-YP874792HU CSB-EP874792HU CSB-BP874792HU CSB-MP874792HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

LZTS2 - TP300824 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

LZTS2 Recombinant Protein Antigen - NBP1-82892PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

LZTS2 Peptide, Human - M34GP09052H from Creative Peptides Category Peptide Source Synthetic. Species Human

Leucine zipper putative tumor suppressor 2 (LZTS2), Recombinant Protein - MBS1342159 from MyBioSource Category Protein Prices $1,470.00, $1,470.00, $1,700.00, $1,700.00, $2,505.00, $2,505.00, $2,950.00, $2,950.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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