LZTS2

Gene Symbol LZTS2
Entrez Gene 84445
Alt Symbol LAPSER1
Species Human
Gene Type protein-coding
Description leucine zipper, putative tumor suppressor 2
Other Description hLZTS2|leucine zipper putative tumor suppressor 2|protein LAPSER1
Swissprots Q8N3I0 D3DR72 Q96JL2 Q96J79 B1AL14 Q9BRK4
Accessions EAW49790 EAW49791 EAW49792 Q9BRK4 AB058716 BAB47442 AK097997 AK298208 BAG60478 AL834338 CAD39005 AY029201 AAK31577 BC005855 AAH05855 BC006212 AAH06212 BC058938 AAH58938 BM544815 CB243010 XM_005270222 XP_005270279 XM_005270223 XP_005270280 XM_005270224 XP_005270281 XM_006718032 XP_006718095 NM_032429 NP_115805
Function Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. {ECO:0000255|HAMAP-Rule:MF_03026, ECO:0000269|PubMed:17000760, ECO:0000269|PubMed:17351128, ECO:0000269|PubMed:17950943, ECO:0000269|PubMed:18490357}.
Subcellular Location Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localized to the centrosome throughout the cell cycle. Localized to the midbody in cells undergoing cytokinesis.
Tissue Specificity Highly expressed in prostate and testis, and at slightly lower levels in spleen, thymus, uterus, small intestine and colon. {ECO:0000269|PubMed:11709705}.

LAPSER1 CRISPR/Cas9 KO Plasmid (h) - sc-410196 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LAPSER1 HDR Plasmid (h) - sc-410196-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LAPSER1 Double Nickase Plasmid (h) - sc-410196-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LAPSER1 Double Nickase Plasmid (h2) - sc-410196-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LAPSER1 CRISPR Activation Plasmid (h) - sc-410196-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LAPSER1 CRISPR Activation Plasmid (h2) - sc-410196-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LAPSER1 Lentiviral Activation Particles (h) - sc-410196-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LAPSER1 Lentiviral Activation Particles (h2) - sc-410196-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LAPSER1 siRNA (h) - sc-62541 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LAPSER1 shRNA Plasmid (h) - sc-62541-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LAPSER1 shRNA (h) Lentiviral Particles - sc-62541-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU149471 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN12884 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12884 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

LZTS2 siRNA (Human) - CRJ3477 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human LZTS2 (NM_032429.2) - SHH336363 from Creative biogene

Category siRNA
Species Reactivities Human

Human LZTS2 siRNA - orb273978 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

LZTS2 shRNA Plasmid (Human) - CHJ3477 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

LZTS2 miRNA 3'UTR clone - MiUTR3H-11234 from Creative biogene

Species Reactivities Human
Search more