LZTS2

Gene Symbol LZTS2
Entrez Gene 84445
Alt Symbol LAPSER1
Species Human
Gene Type protein-coding
Description leucine zipper, putative tumor suppressor 2
Other Description hLZTS2|leucine zipper putative tumor suppressor 2|protein LAPSER1
Swissprots Q8N3I0 D3DR72 Q96JL2 Q96J79 B1AL14 Q9BRK4
Accessions EAW49790 EAW49791 EAW49792 Q9BRK4 AB058716 BAB47442 AK097997 AK298208 BAG60478 AL834338 CAD39005 AY029201 AAK31577 BC005855 AAH05855 BC006212 AAH06212 BC058938 AAH58938 BM544815 CB243010 XM_005270222 XP_005270279 XM_005270223 XP_005270280 XM_005270224 XP_005270281 XM_006718032 XP_006718095 NM_032429 NP_115805
Function Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. {ECO:0000255|HAMAP-Rule:MF_03026, ECO:0000269|PubMed:17000760, ECO:0000269|PubMed:17351128, ECO:0000269|PubMed:17950943, ECO:0000269|PubMed:18490357}.
Subcellular Location Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localized to the centrosome throughout the cell cycle. Localized to the midbody in cells undergoing cytokinesis.
Tissue Specificity Highly expressed in prostate and testis, and at slightly lower levels in spleen, thymus, uterus, small intestine and colon. {ECO:0000269|PubMed:11709705}.

LAPSER1 (B-5) - sc-271958 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
LAPSER1 (B-5): sc-271958. Western blot analysis of LAPSER1 expression in non-transfected: sc-117752 (A) and human LAPSER1 transfected: sc-116591 (B) 293T whole cell lysates.

LAPSER1 (C-19) - sc-67668 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

LAPSER1 (F-11) - sc-365462 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
LAPSER1 (F-11): sc-365462. Western blot analysis of LAPSER1 expression in non-transfected: sc-117752 (A) and human LAPSER1 transfected: sc-116591 (B) 293T whole cell lysates.

LAPSER1 (H-98) - sc-134971 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
LAPSER1 (H-98): sc-134971. Western blot analysis of LAPSER1 expression in non-transfected: sc-117752 (A) and human LAPSER1 transfected: sc-116591 (B) 293T whole cell lysates.

LAPSER1 (P-20) - sc-67669 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LAPSER1 (P-20): sc-67669. Western blot analysis of LAPSER1 expression in non-transfected: sc-117752 (A) and human LAPSER1 transfected: sc-116591 (B) 293T whole cell lysates.

LAPSER1 (T-16) - sc-67671 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LAPSER1 (T-16): sc-67671. Western blot analysis of LAPSER1 expression in Jurkat (A) and K-562 (B) whole cell lysates.

Anti-LZTS2 antibody - ab124191 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of LZTS2 in Human kidney tissue with ab124191 at 20 ug/mL.

Anti-LZTS2 antibody - ab167205 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-LZTS2 antibody (ab167205) at 1/500 dilutionLane 1 : Lysate from 293T cells transfected with LZTS2Lane 2 : non transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG at 2500

Anti-LZTS2 Antibody (aa572-601, AP) - LS-C237332 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LZTS2 Antibody (aa572-601, Biotin) - LS-C237333 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LZTS2 Antibody (aa572-601, APC) - LS-C237334 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LZTS2 Antibody (aa572-601, FITC) - LS-C237335 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LZTS2 Antibody (aa572-601, PE) - LS-C237340 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LZTS2 Antibody (aa572-601, Azide-free, HRP) - LS-C248751 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LZTS2 Antibody - LS-C309192 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-LZTS2 Antibody (aa571-601) - LS-C322789 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LZTS2 Antibody (aa71-120) - LS-C112259 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
LZTS2 antibody LS-C112259 Western blot of Fetal Spleen lysate.

Anti-LZTS2 Antibody (aa572-601) - LS-C163951 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
LZTS2 Antibody western blot of WiDr cell line lysates (35 ug/lane). The LZTS2 antibody detected the LZTS2 protein (arrow).

Anti-LZTS2 Antibody (C-Terminus) IHC-plus™ - LS-B4717 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-LZTS2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4717 concentration 5 ug/ml.

Anti-LZTS2 Antibody (N-Terminus) IHC-plus™ - LS-B9591 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-LZTS2 antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9591 concentration 5 ug/ml.

LZTS2 Antibody - NBP1-58275 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: LZTS2 Antibody [NBP1-58275] - Human Spleen lysate, concentration 0.2-1 ug/ml.

LZTS2 Antibody - NBP1-82892 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: LZTS2 Antibody [NBP1-82892] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10Lane 2: Human Tonsil tissue

LZTS2 Antibody - NBP1-72003 from Novus Biologicals

Prices $399.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: LZTS2 Antibody [NBP1-72003] - Staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

LZTS2 Antibody - H00084445-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: LZTS2 Antibody [H00084445-B01P] - Analysis of LZTS2 expression in transfected 293T cell line by LZTS2 polyclonal antibody. Lane 1: LZTS2 transfected lysate(72.80 KDa). Lane 2: Non-transfected lysate.

LZTS2 Antibody - NBP2-41152 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: LZTS2 Antibody [NBP2-41152] - Western blot analysis of LZTS2 in human kidney tissue lysate with LZTS2 antibody at 1 ug/mL.
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