AASS

Gene Symbol AASS
Entrez Gene 10157
Alt Symbol LKR/SDH, LKRSDH, LORSDH
Species Human
Gene Type protein-coding
Description aminoadipate-semialdehyde synthase
Other Description alpha-aminoadipate semialdehyde synthase|alpha-aminoadipic semialdehyde synthase, mitochondrial|aminoadipic semialdehyde synthase|lysine-2-oxoglutarate reductase|lysine-ketoglutarate reductase /saccharopine dehydrogenase
Swissprots O95462 Q9UDR5
Accessions AAF03526 EAL24343 EAW83564 EAW83565 Q9UDR5 AF229180 AAF44328 AJ007714 CAA07619 AK023446 BAG51195 AK225898 AK294326 BAG57598 BC144246 BC144247 BC156456 AAI56457 BC172503 AAI72503 BM669241 DA995180 XM_011515725 XP_011514027 XM_011515726 XP_011514028 XR_242220 XR_242221 XR_927326 NM_005763 NP_005754
Function Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively.
Subcellular Location Mitochondrion {ECO:0000250}.
Tissue Specificity Expressed in all 16 tissues examined with highest expression in the liver.
Top Pathways Lysine degradation

AASS (G-7) - sc-390536 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AASS (G-7): sc-390536. Western blot analysis of AASS expression in rat liver tissue extract.

AASS (H-5) - sc-390511 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AASS (H-5): sc-390511. Western blot analysis of AASS expression in non-transfected: sc-117752 (A) and mouse AASS transfected: sc-118147 (B) 293T whole cell lysates and rat liver tissue extract (C).

AASS (E-14) - sc-162468 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
AASS (E-14): sc-162468. Western blot analysis of AASS expression in rat liver tissue extract.

AASS (G-13) - sc-162469 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
AASS (G-13): sc-162469. Western blot analysis of AASS expression in HeLa whole cell lysate (A) and rat liver tissue extract (B).

AASS (B-7) - sc-365417 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AASS (B-7): sc-365417. Western blot analysis of AASS expression in non-transfected: sc-117752 (A) and mouse AASS transfected: sc-118147 (B) 293T whole cell lysates.

AASS (D-8) - sc-374322 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AASS (D-8): sc-374322. Western blot analysis of AASS expression in non-transfected: sc-117752 (A) and mouse AASS transfected: sc-118147 (B) 293T whole cell lysates.

AASS (H-300) - sc-134661 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
AASS (H-300): sc-134661. Western blot analysis of AASS expression in non-transfected: sc-117752 (A) and mouse AASS transfected: sc-118147 (B) 293T whole cell lysates.

AASS (Y-16) - sc-162470 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-AASS antibody - ab174488 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-AASS antibody (ab174488) at 1/50 dilution + Mouse liver tissue lysate at 35 µg

Anti-AASS antibody - ab99855 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-AASS antibody (ab99855) at 1/2000 dilutionLane 1 : Human fetal small intestine lysateLane 2 : Human fetal liver lysate

Anti-AASS antibody - ab111754 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-AASS antibody (ab111754) at 1/50 dilution + K562 cell line lysates at 35 µg

Anti-AASS antibody - ab135900 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-AASS antibody (ab135900) at 1/500 dilution + COLO205 cell lysate at 30 µg

Anti-AASS antibody [ EPR9145(B)] - ab154800 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9145(B)
All lanes : Anti-AASS antibody [ EPR9145(B)] (ab154800) at 1/1000 dilutionLane 1 : HeLa lysateLane 2 : Fetal liver lysateLane 3 : HUVEC lysateLane 4 : HepG2 lysateLane 5 : 293T lysateLysates/proteins at 10 µg per lane.

Anti-AASS antibody [EPR9144] - ab151737 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9144
All lanes : Anti-AASS antibody [EPR9144] (ab151737) at 1/1000 dilutionLane 1 : 293T cell lysateLane 2 : HepG2 cell lysateLane 3 : HUVEC cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-AASS / LKR / SDH Antibody (aa251-300) - LS-C119715 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from 293/HUVEC/HeLa cells, using AASS Antibody. The lane on the right is treated with the synthesized peptide.

Anti-AASS / LKR / SDH Antibody (aa268-317) - LS-C187291 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
AASS / LKR / SDH antibody Western Blot of THP-1. Antibody dilution: 1 ug/ml.

Anti-AASS / LKR / SDH Antibody (aa805-834) - LS-C155836 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
AASS Antibody western blot of K562 cell line lysates (35 ug/lane). The AASS antibody detected the AASS protein (arrow).

Anti-AASS / LKR / SDH Antibody (aa243-292) - LS-C200065 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from COLO205 cells using AASS antibody.

Anti-AASS / LKR / SDH Antibody (aa264-294) - LS-C97259 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with the AASS antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

AASS Antibody - NBP1-82833 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

AASS Antibody - NBP1-82832 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: AASS Antibody [NBP1-82832] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

AASS Antibody - NBP1-82831 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: AASS Antibody [NBP1-82831] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).

AASS/LKRSDH Polyclonal Antibody - bs-11391R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-AASS/LKRSDH Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11391R-A350 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-AASS/LKRSDH Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11391R-A488 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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